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Memórias do Instituto Oswaldo Cruz

Print version ISSN 0074-0276On-line version ISSN 1678-8060


CARVALHO, I. T. et al. Vibrio fluvialis attachs to but does not enter Hela cell monolayers. Mem. Inst. Oswaldo Cruz [online]. 1994, vol.89, n.2, pp.221-223. ISSN 0074-0276.

Considering the possibility that invasiveness could be a neglected factor of virulence in Vibrio fluvialis-linked enteritis, since a dysenteric form of the disease was seen in Bangladesh, we studied 12 Brazilian strains of the organism, six clinical and six environmental, to determine whether they might be able to enter into HeLa cell monolayers or would carry plasmids incidentally involved in invasiveness. Four human and two environmental isolates attached to but did not enter into the cells. Though five strains harbored plasmids,no relationship was found between the carriage of these genetic elements and adhesiveness.

Keywords : Vibrio fluvialis; Vibrio pathogenicity; diarrhea; HeLa cell adherence.

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