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Memórias do Instituto Oswaldo Cruz

Print version ISSN 0074-0276On-line version ISSN 1678-8060


OLIVEIRA-NETO, MP; SCHUBACH, A; ARAUJO, ML  and  PIRMEZ, C. High and low doses of antimony (Sbv) in American cutaneous leishmaniasis: a five years follow-up study of 15 patients. Mem. Inst. Oswaldo Cruz [online]. 1996, vol.91, n.2, pp.207-209. ISSN 0074-0276.

Seventeen patients proceeding from the municipality of Rio de Janeiro, Brazil presenting with the cutaneous ulcerative form of American leishmaniasis were treated with one ampoule of pentavalent antimony daily for 30 days. With this regimen the individuals doses varies greatly: from 3.8 mg/kg of body weight to 22.3 mg/kg. After five years, patients receiving either a smaller dose or a bigger one, showed the same therapeutic result: cutaneous scars and no mucosal lesions.

Keywords : cutaneous leishmaniasis; therapy; antimony.

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