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Memórias do Instituto Oswaldo Cruz

Print version ISSN 0074-0276On-line version ISSN 1678-8060


OLIVEIRA, Alexandre Nunes de et al. Immune response in cattle vaccinated against rabies . Mem. Inst. Oswaldo Cruz [online]. 2000, vol.95, n.1, pp.83-88. ISSN 0074-0276.

In order to determine the best type of rabies vaccine to use as a booster, 78 serological samples from singly vaccinated cattle were analyzed by counterimmunoelectrophoresis technique. The animals were divided into several groups, received the first vaccine dose with modified live virus vaccine (ERA strain) and were revaccinated with inactivated virus or modified live virus vaccines. Boosters were given at 2, 4, 8, 12 and 16 weeks following first vaccination. Results showed high titres in the cases of booster with inactivated vaccine. In all cases, however, detectable antibody titres declined quickly.

Keywords : rabies; cattle; vaccination; booster; serology.

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