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vol.95 issue4Nuclear rDNA-based molecular clock of the evolution of triatominae (Hemiptera: Reduviidae), vectors of Chagas diseaseFurther support for a palaearctic origin of Leishmania author indexsubject indexarticles search
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Memórias do Instituto Oswaldo Cruz

Print version ISSN 0074-0276On-line version ISSN 1678-8060


NOYES, HA; MORRISON, DA; CHANCE, ML  and  ELLIS, JT. Evidence for a neotropical origin of Leishmania. Mem. Inst. Oswaldo Cruz [online]. 2000, vol.95, n.4, pp.575-578. ISSN 0074-0276.

Contradictory biogeographic hypotheses for either a Neotropical or a Palaearctic origin of the genus Leishmania have been proposed. Hypotheses constructed on the basis of biogeographic data must be tested against an independent dataset and cannot be supported by biogeographic data alone. In the absence of a fossil record for the Leishmania these two hypotheses were tested against a combined dataset of sequences from the DNA polymerase A catalytic subunit and the RNA polymerase II largest subunit. The phylogeny obtained provided considerable support for a Neotropical origin of the genus Leishmania and leads us to reject the hypothesis for a Palaearctic origin.

Keywords : biogeography; Endotrypanum; Leishmania (Sauroleishmania); DNA polymerase; RNA polymerase.

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