Memórias do Instituto Oswaldo Cruz
Print version ISSN 0074-0276
On-line version ISSN 1678-8060
HULSTIJN, Maarten; OLIVEIRA, Regina Maria F de; MOURA, Egberto G de and MACHADO-SILVA, José Roberto. Lower faecal egg excretion in chemically-induced diabetic mice infected with Schistosoma mansoni due to impaired egg maturation. Mem. Inst. Oswaldo Cruz [online]. 2001, vol.96, n.3, pp.393-396. ISSN 0074-0276. http://dx.doi.org/10.1590/S0074-02762001000300020.
The effect of streptozotocin-induced diabetes mellitus was studied in mice infected with Schistosoma mansoni. Faecal egg excretion was lower in diabetic mice but worm load and total amount of eggs in the intestine tissue were equal to the control group. Evaluation of an oogram showed a great number of immature dead eggs and a low number of mature eggs in diabetic mice. It was therefore concluded that faecal egg excretion was lower in diabetic mice due to impaired egg maturation.
Keywords : Schistosoma mansoni; diabetes mellitus; oogram.