SciELO - Scientific Electronic Library Online

 
vol.101 suppl.1Differential lectin labelling of circulating hemocytes from Biomphalaria glabrata and Biomphalaria tenagophila resistant or susceptible to Schistosoma mansoni infectionChanges induced in Biomphalaria glabrata (Say, 1818) following trials for artificial stimulation of its internal defense system author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Memórias do Instituto Oswaldo Cruz

Print version ISSN 0074-0276

Abstract

BORGES, Claudia Maria da Cunha; AZEVEDO, Carine Machado  and  ANDRADE, Zilton A. A contribution to the pathobiology of Biomphalaria glabrata hemocytes. Mem. Inst. Oswaldo Cruz [online]. 2006, vol.101, suppl.1, pp. 193-198. ISSN 0074-0276.  http://dx.doi.org/10.1590/S0074-02762006000900030.

This study attempts to investigate the relationship between the hemocytes in the two compartments: circulating peripheral lymph and the connective tissues. The hemocytes are compared with the vertebrate macrophages and constitute the principal line of defense against external aggression. The hemocytes were counted in circulating hemolymph and their phagocytic capability was evaluated in Schistosoma mansoni-infected Biomphalaria glabrata and the results were compared with those obtained from normal intact control snails. Although the number of circulating hemocytes revealed a mild increase in snails at the 6th week of infection, the overall findings were similar and pointed out that the cells in the two compartments are not functionally connected. However, the hemocytes found within the connective tissues of infected snails showed definite ultrastructural differences in the number and disposition of cytoplasmic prolongations and organelles in comparison with the hemocytes from non-infected snails. Histochemically, the staining for acid phosphatase activity served as a marker to hemocytes, sometimes being found in extracellular material at the foci of parasite-hemocyte interactions.

Keywords : Biomphalaria glabrata; Schistosoma mansoni; hemocytes.

        · text in English     · pdf in English