SciELO - Scientific Electronic Library Online

vol.102 issue8Evaluation of a modified culture medium for Borrelia burgdorferi sensu latoA thirty years follow-up study on Schistosomiasis mansoni in a community of Minas Gerais, Brazil author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links


Memórias do Instituto Oswaldo Cruz

Print version ISSN 0074-0276On-line version ISSN 1678-8060


FAGUNDES, Aline et al. First encounter of subclinical human Leishmania (Viannia) infection in State of Rio Grande do Sul, Brazil. Mem. Inst. Oswaldo Cruz [online]. 2007, vol.102, n.8, pp.1003-1005. ISSN 0074-0276.

The objective of the present study was to evaluate the specificity of the Montenegro skin test (MST) in an area in Brazil, state of Grande do Sul State (RS), which was considered to be non-endemic for leishmaniasis. Sixty subjects presented a positive MST and were reevaluated by clinical examination, serology and polymerase chain reaction (PCR) of peripheral blood for the detection of subclinical Leishmania infection. None of the subjects presented clinical signs or symptoms of current leishmaniasis or a history of the disease.Leishmania (Viannia) DNA was detected in blood by PCR and hybridization in one subject. The PCR skin test-positive individual remained asymptomatic throughout the study. Clinical examination showed no scars suggestive of past cutaneous leishmaniasis. Human subclinical infection with Leishmania (Viannia) in RS was confirmed by PCR. This is the first report of subclinical infection with this parasite in the human population of this area.

Keywords : Leishmania; PCR; Montenegro skin test; subclinical infection; Rio Grande do Sul; Brazil.

        · text in English     · English ( pdf epdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License