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Memórias do Instituto Oswaldo Cruz
Print version ISSN 0074-0276
On-line version ISSN 1678-8060
SOUZA, Wanderley de. Electron microscopy of trypanosomes: a historical view. Mem. Inst. Oswaldo Cruz [online]. 2008, vol.103, n.4, pp.313-325. ISSN 0074-0276. http://dx.doi.org/10.1590/S0074-02762008000400001.
Since the discovery of the electron microscope and the development of the initial techniques for the processing of biological samples for electron microscopy, the protozoan Trypanosoma cruzi has been the subject of intense investigation. This review analyzes the results obtained by observation of whole trypanosomes as well as thin sections and replicas using several microscopic approaches. Micrographs detailing the appearance of T. cruzi using several methods illustrate the evolution of electron microscopic techniques as well as its contribution to understanding the structural organization of the protozoan.
Keywords : electron microscopy; ultrastructure; trypanosomes; Trypanosoma cruzi.