Memórias do Instituto Oswaldo Cruz
Print version ISSN 0074-0276
GIESE, Viviane et al. Trypanosoma cruzi: a stage-specific calpain-like protein is induced after various kinds of stress. Mem. Inst. Oswaldo Cruz [online]. 2008, vol.103, n.6, pp. 598-601. ISSN 0074-0276. http://dx.doi.org/10.1590/S0074-02762008000600015.
Calpains are calcium-dependent cysteine proteinases found in all living organisms and are involved in diverse cellular processes. Calpain-like proteins have been reported after in silico analysis of the Tritryps genome and are believed to play important roles in cell functions of trypanosomatids. We describe the characterization of a member of this family, which is differentially expressed during the life-cycle of Trypanosoma cruzi.
Keywords : calpain-like; Trypanosoma cruzi; stress; metacyclogenesis.