SciELO - Scientific Electronic Library Online

 
vol.105 número7First report of Angiostrongylus cantonensis (Nematoda: Metastrongylidae) in Achatina fulica (Mollusca: Gastropoda) from Southeast and South BrazilThe anticancer drug tamoxifen is active against Trypanosoma cruzi in vitro but ineffective in the treatment of the acute phase of Chagas disease in mice índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Memórias do Instituto Oswaldo Cruz

versão impressa ISSN 0074-0276

Resumo

SAWANYAWISUTH, Kittisak et al. Peripheral eosinophilia as an indicator of meningitic angiostrongyliasis in exposed individuals. Mem. Inst. Oswaldo Cruz [online]. 2010, vol.105, n.7, pp. 942-944. ISSN 0074-0276.  http://dx.doi.org/10.1590/S0074-02762010000700020.

The diagnosis of meningitic angiostrongyliasis (MA) is based on clinical criteria. A lumbar puncture is used as a diagnostic tool, but it is an invasive procedure. The blood eosinophil levels are also assessed and used in the diagnosis of this disease. We enrolled 47 patients with serologically proven MA and 131 controls with intestinal parasite infections. An absolute eosinophil count model was found to be the best marker for MA. An eosinophil count of more than 798 cells led to sensitivity, specificity, positive predictive and negative predictive values of 76.6%, 80.2%, 58.1% and 90.5%, respectively. These data support the use of testing for high blood eosinophil levels as a diagnostic tool for MA in individuals that are at risk for this disease.

Palavras-chave : eosinophilia; diagnosis; meningitis; angiostrongyliasis; Angiostrongylus cantonensis.

        · texto em Inglês     · pdf em Inglês