Resumo

FIGUEIREDO, Deuseli Quaresma de et al. First report of the bla_OXA-58 gene in a clinical isolate of Acinetobacter baumannii in Rio de Janeiro, Brazil. Mem. Inst. Oswaldo Cruz [online]. 2011, vol.106, n.3, pp. 368-370. ISSN 0074-0276.  http://dx.doi.org/10.1590/S0074-02762011000300019.

Carbapenemase production is an important mechanism of carbapenem resistance among nonfermentative Gram-negative isolates. This study aimed to report the detection of bla_OXA-58 gene in multiresistant clinical isolates of Acinetobacter baumannii recovered from inpatients in a public hospital. Polymerase chain reaction tests were performed to detect the bla_OXA-23-like, bla_OXA-24-like, bla_OXA-58-like and bla_OXA-51-like genes. The bla_OXA-58 and bla_OXA-23 genes were detected in one and three isolates, respectively. Sequencing of the bla_OXA-58-like amplicon revealed 100% identity with the A. baumannii bla_OXA-58 gene listed in the GenBank database. This is the first report of an OXA-58-producing A. baumannii isolate in Rio de Janeiro, Brazil.

Palavras-chave : Acinetobacter baumannii; oxacillinases; OXA-58.