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Memórias do Instituto Oswaldo Cruz

Print version ISSN 0074-0276

Abstract

PEREIRA, Luiza de Oliveira Ramos et al. Severity of tegumentary leishmaniasis is not exclusively associated with Leishmania RNA virus 1 infection in Brazil. Mem. Inst. Oswaldo Cruz [online]. 2013, vol.108, n.5, pp.665-667. ISSN 0074-0276.  https://doi.org/10.1590/0074-0276108052013021.

Leishmania RNA virus (LRV) has been shown to be a symbiotic component of Leishmania parasites in South America. Nested retro-transcription polymerase chain reaction was employed to investigate LRV1 presence in leishmaniasis lesions from Brazil. In endemic areas of Rio de Janeiro (RJ), no LRV1 infection was observed even with mucosal involvement. LRV1 was only detected in Leishmania (V.) guyanensis cutaneous lesions from the northern region, which were obtained from patients presenting with disease reactivation after clinical cure of their primary lesions. Our results indicated that the severity of leishmaniasis in some areas of RJ, where Leishmania (V.) brazi-liensis is the primary etiological agent, was not associated with Leishmania LRV1 infection.

Keywords : Leishmania; LRV; tegumentary leishmaniasis; nested retro-transcription PCR.

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