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Memórias do Instituto Oswaldo Cruz

versão impressa ISSN 0074-0276versão On-line ISSN 1678-8060

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RAMOS, Juliana Nunes et al. Genome sequence of a multidrug-resistant Corynebacterium striatum isolated from bloodstream infection from a nosocomial outbreak in Rio de Janeiro, Brazil. Mem. Inst. Oswaldo Cruz [online]. 2018, vol.113, n.9, e180051.  Epub 10-Jul-2018. ISSN 0074-0276.  http://dx.doi.org/10.1590/0074-02760180051.

Multidrug-resistant (MDR) Corynebacterium striatum has been cited with increased frequency as pathogen of nosocomial infections. In this study, we report the draft genome of a C. striatum isolated from a patient with bloodstream infection in a hospital of Rio de Janeiro, Brazil. The isolate presented susceptibility only to tetracycline, vancomycin and linezolid. The detection of various antibiotic resistance genes is fully consistent with previously observed multidrug-resistant pattern in Corynebacterium spp. A large part of the pTP10 plasmid of MDR C. striatum M82B is present in the genome of our isolate. A SpaDEF cluster and seven arrays of CRISPR-Cas were found.

Palavras-chave : multidrug-resistant; Corynebacterium striatum; bloodstream infection; CRISPR-Cas; spaDEF cluster.

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