Efeito da meditação no nível de estresse psicológico de mulheres com neoplasia mamária: revisão sistemática

Araujo, Raquel Vilanova; Fernandes, Ana Fátima Carvalho; Nery, Inez Sampaio; Andrade, Elaine Maria Leite Rangel; Nogueira, Lídya Tolstenko; Azevedo, Francisco Honeidy Carvalho

doi:10.1590/S1980-220X2018031303529

Raquel Vilanova Araujo Autor correspondente: Raquel Vilanova Araujo, Campus Universitário Ministro Petrônio Portella, Bairro Ininga CEP 64049-550 – Teresina, PI, Brasil ppgenf@ufpi.edu.br

Universidade Federal do Piauí, Departamento de Enfermagem, Teresina, PI, Brasil

http://orcid.org/0000-0002-1752-296X

Ana Fátima Carvalho Fernandes

Universidade Federal do Ceará, Departamento de Enfermagem, Fortaleza, CE, Brasil

http://orcid.org/0000-0001-5110-6364

Inez Sampaio Nery

Universidade Federal do Piauí, Departamento de Enfermagem, Teresina, PI, Brasil

http://orcid.org/0000-0002-7481-2250

Elaine Maria Leite Rangel Andrade

Universidade Federal do Piauí, Departamento de Enfermagem, Teresina, PI, Brasil

http://orcid.org/0000-0002-1772-7439

Lídya Tolstenko Nogueira

Universidade Federal do Piauí, Departamento de Enfermagem, Teresina, PI, Brasil

http://orcid.org/0000-0003-4918-6531

Francisco Honeidy Carvalho Azevedo

Centro Universitário, Teresina, PI, Brasil

http://orcid.org/0000-0002-8431-2022

Autor correspondente: Raquel Vilanova Araujo, Campus Universitário Ministro Petrônio Portella, Bairro Ininga CEP 64049-550 – Teresina, PI, Brasil ppgenf@ufpi.edu.br

Autores/anos	Objetivos
Sarenmalm et al., 2017⁽²⁰20. Sarenmalm Ek, Mårtensson LB, Andersson BA, Karlsson P, Bergh I. Mindfulness and its efficacy for psychological and biological responses in women with breast cancer. Cancer Med. 2017;6(5):1108-22. DOI: http://dx.doi.org/10.1002/cam4.1052 http://dx.doi.org/10.1002/cam4.1052... ⁾	Determinar a eficácia de uma intervenção de meditação mindfulness baseada na redução do estresse (MBSR) para transtornos de humor em mulheres com câncer de mama.
Boyle et al., 2017⁽²¹21. Boyle CC, Stanton AL, Ganz PA, Crespi CM, Bower JE. Improvements in emotion regulation following mindfulness meditation: effects on depressive symptoms and perceived stress in younger breast cancer survivors. J Consult Clin Psychol. 2017;85(4):397-402. DOI: http://dx.doi.org/10.1037/ccp0000186 http://dx.doi.org/10.1037/ccp0000186... ⁾	Testar estratégias de regulação de emoções como mediadores de efeitos da intervenção MBSR em uma amostra de mulheres jovens tratadas de câncer de mama, um grupo de risco para sofrimento psíquico.
Offidani et al., 2017⁽²²22. Offidani E, Peterson JC, Loizzo J, Moore A, Charlson ME. Stress and response to treatment: insights from a pilot study using a 4-week contemplative self-healing meditation intervention for posttraumatic stress in breast cancer. J Evid Based Complementary Altern Med. 2017;22(4):715-20. DOI: http://dx.doi.org/10.1177/2156587217708522 http://dx.doi.org/10.1177/21565872177085... ⁾	Avaliar se o programa Contemplative de autocura tem efeito diferente na redução do estresse pós-traumático entre sobreviventes de câncer de mama com ou sem estresse crônico.
Johns et al., 2016⁽²³23. Johns SA, Brown LF, Beck-Coon K, Talib TL, Monahan PO, Giesler RB, et al. Randomized controlled pilot trial of mindfulness-based stress reduction compared to psychoeducational support for persistently fatigued breast and colorectal cancer survivors. Support Care Cancer. 2016; 24(10):4085-96. DOI: http://dx.doi.org/10.1007/s00520-016-3220- http://dx.doi.org/10.1007/s00520-016-322... ⁾	Comparar MBSR à psicoeducação entre sobreviventes de câncer de mama e colorretal persistentemente fatigados e sintomas associados.
Carlson et al., 2016⁽²⁴24. Carlson LE, Tamagawa R, Stephen J, Drysdale E, Zhong L, Speca M. Randomized-controlled trial of mindfulness-based cancer recovery versus supportive expressive group therapy among distressed breast cancer survivors (MINDSET): long-term follow-up results. Psychooncology. 2016;25(7):750-9. DOI: http://dx.doi.org/10.1002/pon.4150 http://dx.doi.org/10.1002/pon.4150... ⁾	Medir os efeitos de duas intervenções (MBSR) e Terapia de grupo de apoio expressivo (SET) em sobreviventes de câncer de mama.
Bower, 2015⁽²⁵25. Bower JE, Crosswell AD, Stanton AL, Crespi CM, Winston D, Arevalo J, et al. Mindfulness meditation for younger breast cancer survivors: a randomized controlled trial. Cancer. 2015;121(8):1231-40. DOI: http://dx.doi.org/10.1002/cncr.29194 http://dx.doi.org/10.1002/cncr.29194... ⁾	Avaliar a viabilidade e eficácia de uma intervenção MBSR para mulheres que foram diagnosticadas com câncer de mama antes ou aos 50 anos de idade.
Charlson et al., 2014⁽²⁶26. Charlson ME, Loizzo J, Moadel A, Neale M, Newman C, Olivo E, et al. Contemplative self healing in women breast cancer survivors: a pilot study in underserved minority women shows improvement in quality of life and reduced stress. BMC Complement Altern Med. 2014;14:349. DOI: http://dx.doi.org/10.1186/1472-6882-14-349 http://dx.doi.org/10.1186/1472-6882-14-3... ⁾	Avaliar os resultados de um programa contemplativo de autocura de 20 semanas na qualidade de vida de mulheres com câncer de mama.
Lengacher et al., 2014⁽²⁷27. Lengacher CA, Reich RR, Kip KE, Barta M, Ramesar S, Paterson CL, et al. Influence of mindfulness-based stress reduction (MBSR) on telomerase activity in women with breast cancer (BC). Biol Res Nurs. 2014;16(4):438-47. DOI: http://dx.doi.org/10.1177/1099800413519495 http://dx.doi.org/10.1177/10998004135194... ⁾	Investigar os efeitos da meditação MBSR no comprimento dos telômeros e na atividade da telomerase.
Lengacher et al., 2014⁽²⁸28. Lengacher CA, Shelton MM, Reich RR, Barta MK, Johnson-Mallard V, Moscoso MS, et al. Mindfulness based stress reduction (MBSR(BC)) in breast cancer: evaluating fear of recurrence (FOR) as a mediator of psychological and physical symptoms in a randomized control trial (RCT). J Behav Med. 2014;37(2):185-95. DOI: http://dx.doi.org/10.1007/s10865-012-9473-6 http://dx.doi.org/10.1007/s10865-012-947... ⁾	Investigar os mecanismos de ação do MBSR na redução do medo de recorrência e outros mediadores potenciais.
Henderson et al., 2013⁽²⁹29. Henderson VP, Massion AO, Clemow L, Hurley TG, Druker S, Hébert JR. A randomized controlled trial of mindfulness-based stress reduction for women with early-stage breast cancer receiving radiotherapy. Integr Cancer Ther. 2013;12(5):404-13. DOI: http://dx.doi.org/10.1177/1534735412473640 http://dx.doi.org/10.1177/15347354124736... ⁾	Testar a eficácia relativa do MBSR em comparação com uma intervenção de educação nutricional e cuidados habituais em mulheres com câncer de mama em estágio inicial recém-diagnosticadas submetidas à radioterapia.
Calrson et al., 2013⁽³⁰30. Carlson LE, Doll R, Stephen J, Faris P, Tamagawa R, Drysdale E, et al. Randomized controlled trial of Mindfulness-based cancer recovery versus supportive expressive group therapy for distressed survivors of breast cancer (MINDSET). J Clin Oncol. 2013;31(25):3119-26. DOI: http://ascopubs.org/doi/10.1200/JCO.2012.47.5210 http://ascopubs.org/doi/10.1200/JCO.2012... ⁾	Comparar a eficácia de duas intervenções em grupo para ajudar sobreviventes do câncer de mama que enfrentam angústias: o MBSR e a terapia de grupo de apoio expressivo (SET).
Andersen et al., 2013⁽³¹31. Andersen SR, Würtzen H, Steding-Jessen M, Christensen J, Andersen KK, Flyger H, et al. Effect of mindfulness-based stress reduction on sleep quality: results of a randomized trial among Danish breast cancer patients. Acta Oncol. 2013;52(2):336-44. DOI: http://dx.doi.org/10.3109/0284186X.2012.745948 http://dx.doi.org/10.3109/0284186X.2012.... ⁾	Determinar o efeito do programa MBSR na qualidade do sono em pacientes com câncer de mama, na redução do estresse e ondas de calor.
Hoffman et al., 2012⁽³²32. Hoffman CJ, Ersser SJ, Hopkinson JB, Nicholls PG, Harrington JE, Thomas PW. Effectiveness of mindfulness-based stress reduction in mood, breast- and endocrine-related quality of life, and well-being in stage 0 to III breast cancer: a randomized, controlled trial. J Clin Oncol. 2012;30(12):1335-42. DOI: http://dx.doi.org/10.1200/JCO.2010.34.0331 http://dx.doi.org/10.1200/JCO.2010.34.03... ⁾	Avaliar a eficácia do MBSR em relação ao humor, qualidade de vida e bem-estar após tratamento hospitalar em mulheres com câncer de mama estágio 0 a III.
Lengacher et al., 2012⁽³³33. Lengacher CA, Reich RR, Post-White J, Moscoso M, Shelton MM, Barta M, et al. Mindfulness based stress reduction in post-treatment breast cancer patients: an examination of symptoms and symptom clusters. J Behav Med. 2012;35(1):86-94. DOI: http://dx.doi.org/1007/s10865-011-9346-4 http://dx.doi.org/1007/s10865-011-9346-4... ⁾	Investigar a prevalência e gravidade dos sintomas e agrupamento de sintomas em sobreviventes de câncer de mama que participaram do MBSR.
Matousek et al., 2011⁽³⁴34. Matousek RH, Pruessner JC, Dobkin PL. Changes in the cortisol awakening response (CAR) following participation in Mindfulness-Based Stress Reduction in women who completed treatment for breast cancer. Complement Ther Clin Pract. 2011;17(2):65-70. DOI: http://dx.doi.org/10.1016/j.ctcp.2010.10.005 http://dx.doi.org/10.1016/j.ctcp.2010.10... ⁾	Avaliar as mudanças na resposta do nível de cortisol matinal (CAR) após a participação em Programa MBSR em mulheres que completaram o tratamento para câncer de mama.
Lengacher et al., 2011⁽³⁵35. Lengacher CA, Johnson-Mallard V, Barta M, Fitzgerald S, Moscoso MS, Post-White J, et al. Feasibility of a mindfulness-based stress reduction program for early-stage breast cancer survivors. J Holist Nurs. 2011;29(2):107-17. DOI: http://dx.doi.org/10.1177/089801011038593 http://dx.doi.org/10.1177/08980101103859... ⁾	Avaliar o efeito positivo do MBSR sobre o estado psicológico de sobreviventes de câncer de mama, características psicossociais, sintomas e qualidade de vida durante o tratamento até a retomada das atividades diárias.
Matchim et al., 2010⁽³⁶36. Matchim Y, Armer JM, Stewart BR. Effects of mindfulness-based stress reduction (MBSR) on health among breast cancer survivors. West J Nurs Res. 2011;33(8):996-1016. DOI: http://dx.doi.org/10.1177/0193945910385363 http://dx.doi.org/10.1177/01939459103853... ⁾	Examinar os efeitos de um programa MBSR sobre os resultados fisiológicos e psicológicos entre as sobreviventes do câncer de mama em estágio inicial.
Lengacher et al., 2009⁽³⁷37. Lengacher CA, Johnson-Mallard V, Post-White J, Moscoso MS, Jacobsen PB, Klein TW, et al. Randomized controlled trial of mindfulness-based stress reduction (MBSR) for survivors of breast cancer. Psychooncology. 2009;18(12):1261-72. DOI: http://dx.doi.org/10.1002/pon.1529 http://dx.doi.org/10.1002/pon.1529... ⁾	Determinar se uma intervenção de MBSR em comparação com os cuidados habituais é eficaz na melhoria do estado físico e psicológico de sobreviventes de câncer de mama, e se tais efeitos são modificados pela extensão da conformidade com o programa MBSR.
Nidich et al., 2009⁽³⁸38. Nidich SI, Fields JZ, Rainforth MV, Pomerantz R, Cella D, Kristeller J, et al. A randomized controlled trial of the effects of transcendental meditation on quality of life in older breast cancer patients. Integr Cancer Ther. 2009;8(3):228-34. DOI: http://dx.doi.org/10.1177/153473540934300 http://dx.doi.org/10.1177/15347354093430... ⁾	Avaliar o impacto do programa de Meditação Transcendental e o atendimento padrão em comparação com o tratamento padrão sozinho na qualidade de vida (QV) de mulheres idosas (≥55 anos) com câncer de mama, estágio II a IV.
Witek-Janusek et al., 2008⁽³⁹39. Witek-Janusek L, Albuquerque K, Chroniak KR, Chroniak C, Durazo-Arvizu R, Mathews HL. Effect of mindfulness based stress reduction on immune function, quality of life and coping in women newly diagnosed with early stage breast cancer. Brain Behav Immun. 2008;22(6):969-81. DOI: http://dx.doi.org/10.1016/j.bbi.2008.01.012 http://dx.doi.org/10.1016/j.bbi.2008.01.... ⁾	Avaliar o efeito e viabilidade de um programa MBSR sobre a função imune, qualidade de vida e coping em mulheres recentemente diagnosticadas com câncer de mama.
Calson et al., 2007⁽⁴⁰40. Carlson LE, Speca M, Faris P, Patel KD. One year pre–post intervention follow-up of psychological, immune, endocrine and blood pressure outcomes of mindfulness-based stress reduction (MBSR) in breast and prostate cancer outpatients, Brain Behav Immun. 2007;21(8): 1038-49. DOI: https://doi.org/10.1016/j.bbi.2007.04.002 https://doi.org/10.1016/j.bbi.2007.04.00... ⁾	Investigar os efeitos da participação contínua em um programa MBSR na qualidade de vida (QL), sintomas de estresse, humor e parâmetros endócrinos, imunológicos e autonômicos em pacientes com câncer de mama e próstata em estágio inicial.
Carlson et al., 2003⁽⁴¹41. Carlson LE, Speca Michael PSYD, Patel, Kamala D. PHD; Goodey, Eileen MSW. Mindfulness-based stress reduction in relation to quality of life, mood, symptoms of stress, and immune parameters in breast and prostate cancer outpatients. Psychosom Med. 2003;65(4):571-81.⁾	Investigar a relação entre um programa de MBSR para pacientes com câncer de mama e próstata em estágio inicial e a qualidade de vida, estado de humor, sintomas de estresse, contagem de linfócitos e produção de citocinas.

Tipos de meditação e práticas em grupo
Mindfulness-based stress reduction. Kabat-Zinn. Programa de oito semanas de atividades em grupo (meditação, mindfulness, yoga), orientação, prática, domicílio, entrega de manual, CD e diário para registro da prática em domicílio⁽²⁰20. Sarenmalm Ek, Mårtensson LB, Andersson BA, Karlsson P, Bergh I. Mindfulness and its efficacy for psychological and biological responses in women with breast cancer. Cancer Med. 2017;6(5):1108-22. DOI: http://dx.doi.org/10.1002/cam4.1052 http://dx.doi.org/10.1002/cam4.1052... ^–²⁸28. Lengacher CA, Shelton MM, Reich RR, Barta MK, Johnson-Mallard V, Moscoso MS, et al. Mindfulness based stress reduction (MBSR(BC)) in breast cancer: evaluating fear of recurrence (FOR) as a mediator of psychological and physical symptoms in a randomized control trial (RCT). J Behav Med. 2014;37(2):185-95. DOI: http://dx.doi.org/10.1007/s10865-012-9473-6 http://dx.doi.org/10.1007/s10865-012-947... ^,31–³²32. Hoffman CJ, Ersser SJ, Hopkinson JB, Nicholls PG, Harrington JE, Thomas PW. Effectiveness of mindfulness-based stress reduction in mood, breast- and endocrine-related quality of life, and well-being in stage 0 to III breast cancer: a randomized, controlled trial. J Clin Oncol. 2012;30(12):1335-42. DOI: http://dx.doi.org/10.1200/JCO.2010.34.0331 http://dx.doi.org/10.1200/JCO.2010.34.03... ^,³⁴34. Matousek RH, Pruessner JC, Dobkin PL. Changes in the cortisol awakening response (CAR) following participation in Mindfulness-Based Stress Reduction in women who completed treatment for breast cancer. Complement Ther Clin Pract. 2011;17(2):65-70. DOI: http://dx.doi.org/10.1016/j.ctcp.2010.10.005 http://dx.doi.org/10.1016/j.ctcp.2010.10... ^,⁴¹41. Carlson LE, Speca Michael PSYD, Patel, Kamala D. PHD; Goodey, Eileen MSW. Mindfulness-based stress reduction in relation to quality of life, mood, symptoms of stress, and immune parameters in breast and prostate cancer outpatients. Psychosom Med. 2003;65(4):571-81.⁾.
Mindfulness-based stress reduction. Kabat-Zinn. Programa adaptado para 6 semanas de atividades em grupo (meditação, mindfulness, yoga), orientação prática domicílio, entrega de manual, CD e diário para registro da prática em domicílio⁽²⁰20. Sarenmalm Ek, Mårtensson LB, Andersson BA, Karlsson P, Bergh I. Mindfulness and its efficacy for psychological and biological responses in women with breast cancer. Cancer Med. 2017;6(5):1108-22. DOI: http://dx.doi.org/10.1002/cam4.1052 http://dx.doi.org/10.1002/cam4.1052... ^,²⁶26. Charlson ME, Loizzo J, Moadel A, Neale M, Newman C, Olivo E, et al. Contemplative self healing in women breast cancer survivors: a pilot study in underserved minority women shows improvement in quality of life and reduced stress. BMC Complement Altern Med. 2014;14:349. DOI: http://dx.doi.org/10.1186/1472-6882-14-349 http://dx.doi.org/10.1186/1472-6882-14-3... ^,³⁰30. Carlson LE, Doll R, Stephen J, Faris P, Tamagawa R, Drysdale E, et al. Randomized controlled trial of Mindfulness-based cancer recovery versus supportive expressive group therapy for distressed survivors of breast cancer (MINDSET). J Clin Oncol. 2013;31(25):3119-26. DOI: http://ascopubs.org/doi/10.1200/JCO.2012.47.5210 http://ascopubs.org/doi/10.1200/JCO.2012... ^,³⁶36. Matchim Y, Armer JM, Stewart BR. Effects of mindfulness-based stress reduction (MBSR) on health among breast cancer survivors. West J Nurs Res. 2011;33(8):996-1016. DOI: http://dx.doi.org/10.1177/0193945910385363 http://dx.doi.org/10.1177/01939459103853... ^–³⁷37. Lengacher CA, Johnson-Mallard V, Post-White J, Moscoso MS, Jacobsen PB, Klein TW, et al. Randomized controlled trial of mindfulness-based stress reduction (MBSR) for survivors of breast cancer. Psychooncology. 2009;18(12):1261-72. DOI: http://dx.doi.org/10.1002/pon.1529 http://dx.doi.org/10.1002/pon.1529... ⁾.
Mindful Awareness Practices (MAP), da Universidade da Califórnia, em Los Angeles. Seis sessões semanais, em grupo de 2 horas. Apresentação de material teórico sobre meditação mindfulness, relaxamento e conexão mente-corpo⁽²⁵25. Bower JE, Crosswell AD, Stanton AL, Crespi CM, Winston D, Arevalo J, et al. Mindfulness meditation for younger breast cancer survivors: a randomized controlled trial. Cancer. 2015;121(8):1231-40. DOI: http://dx.doi.org/10.1002/cncr.29194 http://dx.doi.org/10.1002/cncr.29194... ^,²⁸28. Lengacher CA, Shelton MM, Reich RR, Barta MK, Johnson-Mallard V, Moscoso MS, et al. Mindfulness based stress reduction (MBSR(BC)) in breast cancer: evaluating fear of recurrence (FOR) as a mediator of psychological and physical symptoms in a randomized control trial (RCT). J Behav Med. 2014;37(2):185-95. DOI: http://dx.doi.org/10.1007/s10865-012-9473-6 http://dx.doi.org/10.1007/s10865-012-947... ⁾.
Meditação contemplativa de autocura. Programa de oito semanas, aula em grupo de 90 minutos. Meditação, respiração consciente, imagens curativas. Fornecido material para leitura, fitas de áudio e diário⁽²²22. Offidani E, Peterson JC, Loizzo J, Moore A, Charlson ME. Stress and response to treatment: insights from a pilot study using a 4-week contemplative self-healing meditation intervention for posttraumatic stress in breast cancer. J Evid Based Complementary Altern Med. 2017;22(4):715-20. DOI: http://dx.doi.org/10.1177/2156587217708522 http://dx.doi.org/10.1177/21565872177085... ^,²⁶26. Charlson ME, Loizzo J, Moadel A, Neale M, Newman C, Olivo E, et al. Contemplative self healing in women breast cancer survivors: a pilot study in underserved minority women shows improvement in quality of life and reduced stress. BMC Complement Altern Med. 2014;14:349. DOI: http://dx.doi.org/10.1186/1472-6882-14-349 http://dx.doi.org/10.1186/1472-6882-14-3... ⁾.
Programa de Meditação Transcendental. Programa de sete etapas de 1 a 1,5 hora. Palestras, entrevista pessoal, instrução, reuniões mensais em grupo e prática em casa⁽³⁸38. Nidich SI, Fields JZ, Rainforth MV, Pomerantz R, Cella D, Kristeller J, et al. A randomized controlled trial of the effects of transcendental meditation on quality of life in older breast cancer patients. Integr Cancer Ther. 2009;8(3):228-34. DOI: http://dx.doi.org/10.1177/153473540934300 http://dx.doi.org/10.1177/15347354093430... ⁾.
Práticas em domicílio
Entrega de material informativo, disco CD e diário para anotação; sessões iniciais de cinco até 20 minutos, 6 dias da semana⁽²⁰20. Sarenmalm Ek, Mårtensson LB, Andersson BA, Karlsson P, Bergh I. Mindfulness and its efficacy for psychological and biological responses in women with breast cancer. Cancer Med. 2017;6(5):1108-22. DOI: http://dx.doi.org/10.1002/cam4.1052 http://dx.doi.org/10.1002/cam4.1052... ^,²⁴24. Carlson LE, Tamagawa R, Stephen J, Drysdale E, Zhong L, Speca M. Randomized-controlled trial of mindfulness-based cancer recovery versus supportive expressive group therapy among distressed breast cancer survivors (MINDSET): long-term follow-up results. Psychooncology. 2016;25(7):750-9. DOI: http://dx.doi.org/10.1002/pon.4150 http://dx.doi.org/10.1002/pon.4150... ^,²⁶26. Charlson ME, Loizzo J, Moadel A, Neale M, Newman C, Olivo E, et al. Contemplative self healing in women breast cancer survivors: a pilot study in underserved minority women shows improvement in quality of life and reduced stress. BMC Complement Altern Med. 2014;14:349. DOI: http://dx.doi.org/10.1186/1472-6882-14-349 http://dx.doi.org/10.1186/1472-6882-14-3... ^,³³33. Lengacher CA, Reich RR, Post-White J, Moscoso M, Shelton MM, Barta M, et al. Mindfulness based stress reduction in post-treatment breast cancer patients: an examination of symptoms and symptom clusters. J Behav Med. 2012;35(1):86-94. DOI: http://dx.doi.org/1007/s10865-011-9346-4 http://dx.doi.org/1007/s10865-011-9346-4... ^–³⁶36. Matchim Y, Armer JM, Stewart BR. Effects of mindfulness-based stress reduction (MBSR) on health among breast cancer survivors. West J Nurs Res. 2011;33(8):996-1016. DOI: http://dx.doi.org/10.1177/0193945910385363 http://dx.doi.org/10.1177/01939459103853... ^,³⁸38. Nidich SI, Fields JZ, Rainforth MV, Pomerantz R, Cella D, Kristeller J, et al. A randomized controlled trial of the effects of transcendental meditation on quality of life in older breast cancer patients. Integr Cancer Ther. 2009;8(3):228-34. DOI: http://dx.doi.org/10.1177/153473540934300 http://dx.doi.org/10.1177/15347354093430... ^,⁴¹41. Carlson LE, Speca Michael PSYD, Patel, Kamala D. PHD; Goodey, Eileen MSW. Mindfulness-based stress reduction in relation to quality of life, mood, symptoms of stress, and immune parameters in breast and prostate cancer outpatients. Psychosom Med. 2003;65(4):571-81.⁾.
Incentivo à prática formal (meditação sentado, deitado, caminhando e movimento consciente e informal de meditação (consciência e atenção nas atividades do dia a dia, alimentação, deslocamentos, conversas etc.)⁽²⁷27. Lengacher CA, Reich RR, Kip KE, Barta M, Ramesar S, Paterson CL, et al. Influence of mindfulness-based stress reduction (MBSR) on telomerase activity in women with breast cancer (BC). Biol Res Nurs. 2014;16(4):438-47. DOI: http://dx.doi.org/10.1177/1099800413519495 http://dx.doi.org/10.1177/10998004135194... ^–²⁸28. Lengacher CA, Shelton MM, Reich RR, Barta MK, Johnson-Mallard V, Moscoso MS, et al. Mindfulness based stress reduction (MBSR(BC)) in breast cancer: evaluating fear of recurrence (FOR) as a mediator of psychological and physical symptoms in a randomized control trial (RCT). J Behav Med. 2014;37(2):185-95. DOI: http://dx.doi.org/10.1007/s10865-012-9473-6 http://dx.doi.org/10.1007/s10865-012-947... ^,³⁰30. Carlson LE, Doll R, Stephen J, Faris P, Tamagawa R, Drysdale E, et al. Randomized controlled trial of Mindfulness-based cancer recovery versus supportive expressive group therapy for distressed survivors of breast cancer (MINDSET). J Clin Oncol. 2013;31(25):3119-26. DOI: http://ascopubs.org/doi/10.1200/JCO.2012.47.5210 http://ascopubs.org/doi/10.1200/JCO.2012... ^,³⁴34. Matousek RH, Pruessner JC, Dobkin PL. Changes in the cortisol awakening response (CAR) following participation in Mindfulness-Based Stress Reduction in women who completed treatment for breast cancer. Complement Ther Clin Pract. 2011;17(2):65-70. DOI: http://dx.doi.org/10.1016/j.ctcp.2010.10.005 http://dx.doi.org/10.1016/j.ctcp.2010.10... ^,³⁷37. Lengacher CA, Johnson-Mallard V, Post-White J, Moscoso MS, Jacobsen PB, Klein TW, et al. Randomized controlled trial of mindfulness-based stress reduction (MBSR) for survivors of breast cancer. Psychooncology. 2009;18(12):1261-72. DOI: http://dx.doi.org/10.1002/pon.1529 http://dx.doi.org/10.1002/pon.1529... ⁾.
*Follow-up*
Dois meses⁽²⁰20. Sarenmalm Ek, Mårtensson LB, Andersson BA, Karlsson P, Bergh I. Mindfulness and its efficacy for psychological and biological responses in women with breast cancer. Cancer Med. 2017;6(5):1108-22. DOI: http://dx.doi.org/10.1002/cam4.1052 http://dx.doi.org/10.1002/cam4.1052... ^–²³23. Johns SA, Brown LF, Beck-Coon K, Talib TL, Monahan PO, Giesler RB, et al. Randomized controlled pilot trial of mindfulness-based stress reduction compared to psychoeducational support for persistently fatigued breast and colorectal cancer survivors. Support Care Cancer. 2016; 24(10):4085-96. DOI: http://dx.doi.org/10.1007/s00520-016-3220- http://dx.doi.org/10.1007/s00520-016-322... ^,²⁶26. Charlson ME, Loizzo J, Moadel A, Neale M, Newman C, Olivo E, et al. Contemplative self healing in women breast cancer survivors: a pilot study in underserved minority women shows improvement in quality of life and reduced stress. BMC Complement Altern Med. 2014;14:349. DOI: http://dx.doi.org/10.1186/1472-6882-14-349 http://dx.doi.org/10.1186/1472-6882-14-3... ^,²⁹29. Henderson VP, Massion AO, Clemow L, Hurley TG, Druker S, Hébert JR. A randomized controlled trial of mindfulness-based stress reduction for women with early-stage breast cancer receiving radiotherapy. Integr Cancer Ther. 2013;12(5):404-13. DOI: http://dx.doi.org/10.1177/1534735412473640 http://dx.doi.org/10.1177/15347354124736... ^–³⁰30. Carlson LE, Doll R, Stephen J, Faris P, Tamagawa R, Drysdale E, et al. Randomized controlled trial of Mindfulness-based cancer recovery versus supportive expressive group therapy for distressed survivors of breast cancer (MINDSET). J Clin Oncol. 2013;31(25):3119-26. DOI: http://ascopubs.org/doi/10.1200/JCO.2012.47.5210 http://ascopubs.org/doi/10.1200/JCO.2012... ^,³²32. Hoffman CJ, Ersser SJ, Hopkinson JB, Nicholls PG, Harrington JE, Thomas PW. Effectiveness of mindfulness-based stress reduction in mood, breast- and endocrine-related quality of life, and well-being in stage 0 to III breast cancer: a randomized, controlled trial. J Clin Oncol. 2012;30(12):1335-42. DOI: http://dx.doi.org/10.1200/JCO.2010.34.0331 http://dx.doi.org/10.1200/JCO.2010.34.03... ^,³⁴34. Matousek RH, Pruessner JC, Dobkin PL. Changes in the cortisol awakening response (CAR) following participation in Mindfulness-Based Stress Reduction in women who completed treatment for breast cancer. Complement Ther Clin Pract. 2011;17(2):65-70. DOI: http://dx.doi.org/10.1016/j.ctcp.2010.10.005 http://dx.doi.org/10.1016/j.ctcp.2010.10... ^–³⁶36. Matchim Y, Armer JM, Stewart BR. Effects of mindfulness-based stress reduction (MBSR) on health among breast cancer survivors. West J Nurs Res. 2011;33(8):996-1016. DOI: http://dx.doi.org/10.1177/0193945910385363 http://dx.doi.org/10.1177/01939459103853... ^,⁴¹41. Carlson LE, Speca Michael PSYD, Patel, Kamala D. PHD; Goodey, Eileen MSW. Mindfulness-based stress reduction in relation to quality of life, mood, symptoms of stress, and immune parameters in breast and prostate cancer outpatients. Psychosom Med. 2003;65(4):571-81.⁾
Seis semanas⁽²⁴24. Carlson LE, Tamagawa R, Stephen J, Drysdale E, Zhong L, Speca M. Randomized-controlled trial of mindfulness-based cancer recovery versus supportive expressive group therapy among distressed breast cancer survivors (MINDSET): long-term follow-up results. Psychooncology. 2016;25(7):750-9. DOI: http://dx.doi.org/10.1002/pon.4150 http://dx.doi.org/10.1002/pon.4150... ^–²⁵25. Bower JE, Crosswell AD, Stanton AL, Crespi CM, Winston D, Arevalo J, et al. Mindfulness meditation for younger breast cancer survivors: a randomized controlled trial. Cancer. 2015;121(8):1231-40. DOI: http://dx.doi.org/10.1002/cncr.29194 http://dx.doi.org/10.1002/cncr.29194... ^,²⁷27. Lengacher CA, Reich RR, Kip KE, Barta M, Ramesar S, Paterson CL, et al. Influence of mindfulness-based stress reduction (MBSR) on telomerase activity in women with breast cancer (BC). Biol Res Nurs. 2014;16(4):438-47. DOI: http://dx.doi.org/10.1177/1099800413519495 http://dx.doi.org/10.1177/10998004135194... ^,³⁰30. Carlson LE, Doll R, Stephen J, Faris P, Tamagawa R, Drysdale E, et al. Randomized controlled trial of Mindfulness-based cancer recovery versus supportive expressive group therapy for distressed survivors of breast cancer (MINDSET). J Clin Oncol. 2013;31(25):3119-26. DOI: http://ascopubs.org/doi/10.1200/JCO.2012.47.5210 http://ascopubs.org/doi/10.1200/JCO.2012... ^,³³33. Lengacher CA, Reich RR, Post-White J, Moscoso M, Shelton MM, Barta M, et al. Mindfulness based stress reduction in post-treatment breast cancer patients: an examination of symptoms and symptom clusters. J Behav Med. 2012;35(1):86-94. DOI: http://dx.doi.org/1007/s10865-011-9346-4 http://dx.doi.org/1007/s10865-011-9346-4... ^,³⁷37. Lengacher CA, Johnson-Mallard V, Post-White J, Moscoso MS, Jacobsen PB, Klein TW, et al. Randomized controlled trial of mindfulness-based stress reduction (MBSR) for survivors of breast cancer. Psychooncology. 2009;18(12):1261-72. DOI: http://dx.doi.org/10.1002/pon.1529 http://dx.doi.org/10.1002/pon.1529... ^,⁴⁰40. Carlson LE, Speca M, Faris P, Patel KD. One year pre–post intervention follow-up of psychological, immune, endocrine and blood pressure outcomes of mindfulness-based stress reduction (MBSR) in breast and prostate cancer outpatients, Brain Behav Immun. 2007;21(8): 1038-49. DOI: https://doi.org/10.1016/j.bbi.2007.04.002 https://doi.org/10.1016/j.bbi.2007.04.00... ⁾
Quatro meses, 12 meses e 24 meses⁽²²22. Offidani E, Peterson JC, Loizzo J, Moore A, Charlson ME. Stress and response to treatment: insights from a pilot study using a 4-week contemplative self-healing meditation intervention for posttraumatic stress in breast cancer. J Evid Based Complementary Altern Med. 2017;22(4):715-20. DOI: http://dx.doi.org/10.1177/2156587217708522 http://dx.doi.org/10.1177/21565872177085... ⁾
Três meses⁽²⁸28. Lengacher CA, Shelton MM, Reich RR, Barta MK, Johnson-Mallard V, Moscoso MS, et al. Mindfulness based stress reduction (MBSR(BC)) in breast cancer: evaluating fear of recurrence (FOR) as a mediator of psychological and physical symptoms in a randomized control trial (RCT). J Behav Med. 2014;37(2):185-95. DOI: http://dx.doi.org/10.1007/s10865-012-9473-6 http://dx.doi.org/10.1007/s10865-012-947... ⁾
Dezoito horas⁽³⁸38. Nidich SI, Fields JZ, Rainforth MV, Pomerantz R, Cella D, Kristeller J, et al. A randomized controlled trial of the effects of transcendental meditation on quality of life in older breast cancer patients. Integr Cancer Ther. 2009;8(3):228-34. DOI: http://dx.doi.org/10.1177/153473540934300 http://dx.doi.org/10.1177/15347354093430... ⁾
Dois meses, seis meses e 12 meses⁽³¹31. Andersen SR, Würtzen H, Steding-Jessen M, Christensen J, Andersen KK, Flyger H, et al. Effect of mindfulness-based stress reduction on sleep quality: results of a randomized trial among Danish breast cancer patients. Acta Oncol. 2013;52(2):336-44. DOI: http://dx.doi.org/10.3109/0284186X.2012.745948 http://dx.doi.org/10.3109/0284186X.2012.... ⁾
Profissionais que conduziram a intervenção
Médico e psicólogo com experiência em MBSR⁽²³23. Johns SA, Brown LF, Beck-Coon K, Talib TL, Monahan PO, Giesler RB, et al. Randomized controlled pilot trial of mindfulness-based stress reduction compared to psychoeducational support for persistently fatigued breast and colorectal cancer survivors. Support Care Cancer. 2016; 24(10):4085-96. DOI: http://dx.doi.org/10.1007/s00520-016-3220- http://dx.doi.org/10.1007/s00520-016-322... ^,²⁶26. Charlson ME, Loizzo J, Moadel A, Neale M, Newman C, Olivo E, et al. Contemplative self healing in women breast cancer survivors: a pilot study in underserved minority women shows improvement in quality of life and reduced stress. BMC Complement Altern Med. 2014;14:349. DOI: http://dx.doi.org/10.1186/1472-6882-14-349 http://dx.doi.org/10.1186/1472-6882-14-3... ^,²⁸28. Lengacher CA, Shelton MM, Reich RR, Barta MK, Johnson-Mallard V, Moscoso MS, et al. Mindfulness based stress reduction (MBSR(BC)) in breast cancer: evaluating fear of recurrence (FOR) as a mediator of psychological and physical symptoms in a randomized control trial (RCT). J Behav Med. 2014;37(2):185-95. DOI: http://dx.doi.org/10.1007/s10865-012-9473-6 http://dx.doi.org/10.1007/s10865-012-947... ^,³⁰30. Carlson LE, Doll R, Stephen J, Faris P, Tamagawa R, Drysdale E, et al. Randomized controlled trial of Mindfulness-based cancer recovery versus supportive expressive group therapy for distressed survivors of breast cancer (MINDSET). J Clin Oncol. 2013;31(25):3119-26. DOI: http://ascopubs.org/doi/10.1200/JCO.2012.47.5210 http://ascopubs.org/doi/10.1200/JCO.2012... ^–³¹31. Andersen SR, Würtzen H, Steding-Jessen M, Christensen J, Andersen KK, Flyger H, et al. Effect of mindfulness-based stress reduction on sleep quality: results of a randomized trial among Danish breast cancer patients. Acta Oncol. 2013;52(2):336-44. DOI: http://dx.doi.org/10.3109/0284186X.2012.745948 http://dx.doi.org/10.3109/0284186X.2012.... ⁾
Psiquiatra com experiência em MBSR⁽²¹21. Boyle CC, Stanton AL, Ganz PA, Crespi CM, Bower JE. Improvements in emotion regulation following mindfulness meditation: effects on depressive symptoms and perceived stress in younger breast cancer survivors. J Consult Clin Psychol. 2017;85(4):397-402. DOI: http://dx.doi.org/10.1037/ccp0000186 http://dx.doi.org/10.1037/ccp0000186... ⁾
Instrutores certificados⁽²⁰20. Sarenmalm Ek, Mårtensson LB, Andersson BA, Karlsson P, Bergh I. Mindfulness and its efficacy for psychological and biological responses in women with breast cancer. Cancer Med. 2017;6(5):1108-22. DOI: http://dx.doi.org/10.1002/cam4.1052 http://dx.doi.org/10.1002/cam4.1052... ^,³⁰30. Carlson LE, Doll R, Stephen J, Faris P, Tamagawa R, Drysdale E, et al. Randomized controlled trial of Mindfulness-based cancer recovery versus supportive expressive group therapy for distressed survivors of breast cancer (MINDSET). J Clin Oncol. 2013;31(25):3119-26. DOI: http://ascopubs.org/doi/10.1200/JCO.2012.47.5210 http://ascopubs.org/doi/10.1200/JCO.2012... ^,³⁸38. Nidich SI, Fields JZ, Rainforth MV, Pomerantz R, Cella D, Kristeller J, et al. A randomized controlled trial of the effects of transcendental meditation on quality of life in older breast cancer patients. Integr Cancer Ther. 2009;8(3):228-34. DOI: http://dx.doi.org/10.1177/153473540934300 http://dx.doi.org/10.1177/15347354093430... ⁾
Pesquisador qualificado, instrutor de MBSR, no Centro de Atenção Plena da Universidade de Massachusetts⁽³²32. Hoffman CJ, Ersser SJ, Hopkinson JB, Nicholls PG, Harrington JE, Thomas PW. Effectiveness of mindfulness-based stress reduction in mood, breast- and endocrine-related quality of life, and well-being in stage 0 to III breast cancer: a randomized, controlled trial. J Clin Oncol. 2012;30(12):1335-42. DOI: http://dx.doi.org/10.1200/JCO.2010.34.0331 http://dx.doi.org/10.1200/JCO.2010.34.03... ⁾

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[1] Autor correspondente: Raquel Vilanova Araujo, Campus Universitário Ministro Petrônio Portella, Bairro Ininga CEP 64049-550 – Teresina, PI, Brasil ppgenf@ufpi.edu.br

Brasil

Brasil

Efeito da meditação no nível de estresse psicológico de mulheres com neoplasia mamária: revisão sistemática

Efecto de la meditación en el nivel de estrés psicológico de mujeres con neoplasia mamaria: revisión sistemática

RESUMO

Objetivo:

Método:

Resultados:

Conclusão:

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