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Pesquisa Agropecuária Brasileira

versão impressa ISSN 0100-204Xversão On-line ISSN 1678-3921

Resumo

PAIM, Tiago do Prado et al. Detection and evaluation of selection signatures in sheep. Pesq. agropec. bras. [online]. 2018, vol.53, n.5, pp.527-539. ISSN 1678-3921.  https://doi.org/10.1590/s0100-204x2018000500001.

The recent development of genome-wide single nucleotide polymorphism (SNP) arrays made it possible to carry out several studies with different species. The selection process can increase or reduce allelic (or genic) frequencies at specific loci in the genome, besides dragging neighboring alleles in the chromosome. This way, genomic regions with increased frequencies of specific alleles are formed, caracterizing selection signatures or selective sweeps. The detection of these signatures is important to characterize genetic resources, as well as to identify genes or regions involved in the control and expression of important production and economic traits. Sheep are an important species for theses studies as they are dispersed worldwide and have great phenotypic diversity. Due to the large amounts of genomic data generated, specific statistical methods and softwares are necessary for the detection of selection signatures. Therefore, the objectives of this review are to address the main statistical methods and softwares currently used for the analysis of genomic data and the identification of selection signatures; to describe the results of recent works published on selection signatures in sheep; and to discuss some challenges and opportunities in this research field.

Palavras-chave : Ovis aries; analysis software; animal genetic resources; genetic improvement; genomics; molecular genetics; SNP markers.

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