Resumen

CHRISTOVAO, Marília Tavares; CAMPOS, Tarcisio Passos Ribeiro de  y  TRINDADE, Bruno Machado. Simulation and dosimetric analysis of proton and carbon ion therapy in the treatment of uveal melanoma. Radiol Bras [online]. 2011, vol.44, n.6, pp. 367-373. ISSN 0100-3984.  http://dx.doi.org/10.1590/S0100-39842011000600008.

OBJECTIVE: The present paper addresses the dosimetric evaluation of carbon ion radiotherapy as compared with proton therapy. MATERIALS AND METHODS: Computer simulations were undertaken with the Geant4 (GEometry ANd Tracking) code. An eye model discretized into voxels and implemented in the Siscodes system (computer system for dosimetry in radiation therapy) was utilized to generate and superimpose depth dose profiles and isodose curves. Different values for beam energy were adopted in the simulations of carbon ion beams, while in the simulation with proton beams irradiation line devices were included with different absorbing material thicknesses. RESULTS: The simulations outputs were processed and integrated into the Siscodes to generate the spatial dose distribution in the eye model, considering changes in the beam entrance position. The dose rates were normalized as a function of the maximum dose for a beam at a specific entrance position, incident particle energy and number of incident carbon ions and protons. CONCLUSION: The described benefits together with the presented results contribute to the development of clinical applications and researches on carbon ion and proton therapy.

Palabras llave : Carbon ion therapy; Proton therapy; Geant4; Siscodes.