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Química Nova

Print version ISSN 0100-4042On-line version ISSN 1678-7064

Abstract

CARVALHO, Rosangela M. de; RATH, Susanne  and  KUBOTA, Lauro T.. SPR: New tool for biosensors. Quím. Nova [online]. 2003, vol.26, n.1, pp.97-104. ISSN 0100-4042.  http://dx.doi.org/10.1590/S0100-40422003000100017.

This paper reviewed the development and theoretical aspects of surface plasmon ressonance (SPR) technique and discusses this powerful sensor technology in the development of biosensors, as well as for the investigation of biological interactions and clinical assays. The SPR has been proven to be a valuable tool to investigate dynamic processes, such as adsorption, degradation, determination of dieletric properties, association/dissociation kinetics, affinity constants of specific ligand-ligate interactions, allowing real-time analysis at almost any surface. The SPR as a complementary technique alongside electrochemical methods is also presented.

Keywords : surface plasmon ressonance-SPR; electrochemistry; biosensors and biomolecules interactions.

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