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Química Nova

Print version ISSN 0100-4042On-line version ISSN 1678-7064


SILVA, César R.; JARDIM, Isabel C. S. F.; COLLINS, Carol H.  and  AIROLDI, Claudio. New stationary phases based on silica for high performance liquid chromatography. Quím. Nova [online]. 2004, vol.27, n.2, pp.270-276. ISSN 0100-4042.

The present work reviews recent advances in the preparation of new reversed phase packing materials such as sterically protected, bidentate, hybrid organic-inorganic and monolithic phases and phases containing embedded polar groups. The bonding chemistry involved in the preparation of these phases as well as their advantages over conventional C8 and C18 reversed phases are discussed. Understanding the reasons behind the development of these newer column packings helps analysts select the best stationary phase for a given application.

Keywords : stationary phases; embedded phases; HPLC.

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