versión On-line ISSN 1678-7064
GASPAROTTO JR., Arquimedes et al. Phytochemical study and evaluation of the molluscicidal activity of Calophyllum brasiliense Camb (Clusiaceae). Quím. Nova [online]. 2005, vol.28, n.4, pp. 575-578. ISSN 1678-7064. http://dx.doi.org/10.1590/S0100-40422005000400003.
The bioassay-guided fractionation against Biomphalaria glabrata of hydroalcoholic extracts of Calophyllum brasiliense aerial parts led to the isolation of the coumarin, named (-) mammea A/BB. The compound had its structure determined by both spectroscopic techniques (NMR 1H, NMR 13C, gHSQC, gHMBC and MS) and some literature comparison data. The probit analysis of (-) mammea A/BB showed LD50 = 0.67 ppm and LD90 = 1.47 ppm. In addition, the dichloromethane extract obtained from C. brasiliense leaves with significant molluscicidal activity against Biomphalaria glabrata was analyzed by HPLC-UV.
Palabras clave : Calophyllum brasiliense; molluscicidal activity; coumarin.