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Química Nova

versión impresa ISSN 0100-4042versión On-line ISSN 1678-7064


GASPAROTTO JR., Arquimedes et al. Phytochemical study and evaluation of the molluscicidal activity of Calophyllum brasiliense Camb (Clusiaceae). Quím. Nova [online]. 2005, vol.28, n.4, pp.575-578. ISSN 0100-4042.

The bioassay-guided fractionation against Biomphalaria glabrata of hydroalcoholic extracts of Calophyllum brasiliense aerial parts led to the isolation of the coumarin, named (-) mammea A/BB. The compound had its structure determined by both spectroscopic techniques (NMR 1H, NMR 13C, gHSQC, gHMBC and MS) and some literature comparison data. The probit analysis of (-) mammea A/BB showed LD50 = 0.67 ppm and LD90 = 1.47 ppm. In addition, the dichloromethane extract obtained from C. brasiliense leaves with significant molluscicidal activity against Biomphalaria glabrata was analyzed by HPLC-UV.

Palabras clave : Calophyllum brasiliense; molluscicidal activity; coumarin.

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