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Química Nova

Print version ISSN 0100-4042On-line version ISSN 1678-7064


ALMEIDA, Maria Mozarina Beserra et al. Occurrence and biological activity of quassinoids in the last decade. Quím. Nova [online]. 2007, vol.30, n.4, pp.935-951. ISSN 0100-4042.

Quassinoids, the bitter principles of the Simaroubaceae family, are a group of structurally complex and highly oxygenated degraded triterpenes. They are divided into five groups according to their basic skeleton, C-18, C-19, C-20, C-22 and C-25. In recent years, attention has been focused on quassinoids because several of them have shown promising biological activities. This paper features a review of some characteristics of these compounds, updating known information with discoveries from the last decade and covering chemical structures, basic skeletons, occurrence in genus and species, besides detailed studies of biological activities such as antitumor, antimalarial, phytotoxic, antifeedant, insecticidal, anti-inflammatory and antiulcer.

Keywords : quassinoid; molecular structure; biological activities.

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