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Química Nova

Print version ISSN 0100-4042On-line version ISSN 1678-7064

Abstract

KUMMROW, Fábio  and  UMBUZEIRO, Gisela de Aragão. 2-phenylbenzotriazoles (PBTAs): a new class of environmental contaminants. Quím. Nova [online]. 2008, vol.31, n.2, pp.401-406. ISSN 0100-4042.  http://dx.doi.org/10.1590/S0100-40422008000200037.

This work is a literature review of PBTAs, the phenylbenzotriazoles generated from the reduction and chlorination of azo dyes. The PBTAs and the non- chlorinated PBTAs were isolated for the first time from river blue rayon organic extracts that showed high mutagenic activity in the Salmonella/microsome genotoxicity assay. To date, 8 PBTAs have been identified and beside their mutagenic activity in bacteria they cause genotoxic effects in fish and mammalian cell cultures. Due to the large number of textile dyeing facilities in Brazil, studies to determine them in the aquatic environment seem to be relevant.

Keywords : 2-phenylbenzotriazole-type mutagens; PBTAs; genotoxic environmental contaminants.

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