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Química Nova

Print version ISSN 0100-4042On-line version ISSN 1678-7064


COSTA, Emmanoel Vilaça et al. Antimicrobial and antileishmanial activity of essential oil from the leaves of Annona foetida (Annonaceae). Quím. Nova [online]. 2009, vol.32, n.1, pp.78-81. ISSN 1678-7064.

bicyclogermacrene (35.12%), (E)-caryophyllene (14.19%) and α-copaene (8.19%). The antimicrobial and antileishmanial activities were investigated. The oil showed potent antimicrobial activity against Candida albicans and Rhodococcus equi. The oil also showed significant antileishmanial activity, giving the best results against Leishmania guyanensis. A preliminary cytotoxicity assay for this oil was carried out on hamster and mice (Balb/c) peritoneal macrophages. The results obtained were similar to pentamidine and considered not to be cytotoxic to macrophages.

Keywords : Annona foetida; antimicrobial and antileishmanial activities; essential oil composition.

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