SciELO - Scientific Electronic Library Online

vol.32 issue2Antioxidant activity of extracts and condensed tannins from leaves of Maytenus ilicifolia Mart. ex Reiss.Comprehensive two-dimensional gas chromatography (GC × GC) author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links


Química Nova

Print version ISSN 0100-4042On-line version ISSN 1678-7064


CICCIO, José F.; CHAVERRI, Carlos  and  DIAZ, Cecilia. Volatile compounds of Nectandra salicina (lauraceae) from Costa Rica and their cytotoxic activity on cell lines. Quím. Nova [online]. 2009, vol.32, n.2, pp.417-420. ISSN 0100-4042.

The chemical composition of the volatiles of Nectandra salicina growing wild in Costa Rica was determined by capillary GC/FID and GC/MS. Thirty-seven and forty-two compounds were identified in the leaf and branch oils respectively corresponding to about 92.6 and 86.2% of the total amount of the oils. The major components of the leaf oil were: atractylone (14.6%), viridiflorene (10.1%), α-pinene (9.4%), β-caryophyllene (7.2%), α-humulene (7.0%), δ-cadinene (6.1%), β-pinene (6.0%) and germacrene D (5.8%). The major components of the branch oil were: atractylone (21.1%), germacrene D (10.7%), viridiflorene (7.9%) and 7-epi-α-selinene (5.0%). When the oils were tested on different cell lines, all the LD50 values were higher than 150 µg/mL, with values very similar for the leaf and branch oils. Low toxicity could be explained by antagonistic effects among the main compounds present in the oils.

Keywords : Nectandra salicina; volatiles; cytotoxicity.

        · text in English     · English ( pdf epdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License