Abstract

PRAJAPATI, Ashishkumar Kantilal  and  MODI, Vishal Pankajkumar. Synthesis and biological activity of n-{5-(4-methylphenyl) diazenyl-4-phenyl-1, 3-thiazol-2-yl}benzamide derivatives. Quím. Nova [online]. 2011, vol.34, n.5, pp. 771-774. ISSN 0100-4042.  http://dx.doi.org/10.1590/S0100-40422011000500008.

In the present study, various amides of 2-amino-5-(4-methylphenyl)-diazenyl-4-phenyl-1, 3-thiazole was synthesized and their biological activities were evaluated. All the synthesized compounds were characterized by the combination of elemental analysis and standard spectroscopic methods. They are screened for anti-bacterial activity against Escherichia coli and Staphylococcus aureus as well as screened for antifungal activity against Aspergillus niger and Apergillus oryzae by cup plate method at 1 µg/ mL concentration in DMF.

Keywords : aminothiazole derivatives; amide linkage; microbial activity.