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Química Nova

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MENDES, Adriano A.; OLIVEIRA, Pedro C. de; CASTRO, Heizir F. de  and  GIORDANO, Raquel de L. C.. Application of chitosan as support for immobilization of enzymes of industrial interest. Quím. Nova [online]. 2011, vol.34, n.5, pp.831-840. ISSN 0100-4042.

Chitosan, poly[β-(1-4)-linked-2-amino-2-deoxy-D-glucose], is the N-deacetylated product of chitin which is a major component of arthropod and crustacean shells such as lobsters, crabs, shrimps, and cuttlefishes. In addition, chitosan has many significant biological and chemical properties such as biodegradability, biocompatibility and bioactivity as well as polycationic properties. Thus, it has been widely used in many industrial and biomedical applications including wastewater treatment, chromatographic support, carriers for controlled drug delivery and enzyme immobilization. This review is an insight into the exploitation of utilization of chitosan based-supports in different geometrical configurations on the immobilization of enzymes by different protocols for further application in biotransformation reactions.

Keywords : chitosan; immobilization; enzymes.

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