On-line version ISSN 1678-4618
KHAN, F.. Polarographic study and electrode kinetics of [Zn(II) - antibiotics - cephaloglycin] system vis a vis kinetics of electrode reactions. Eclet. Quím. [online]. 2008, vol.33, n.3, pp. 59-68. ISSN 1678-4618. http://dx.doi.org/10.1590/S0100-46702008000300009.
Electrode kinetics and complex formation of Zn(II) using doxycycline, chlortetracycline, oxytetracycline, tetracycline, minocycline, amoxicillin, chloramphenicol and cephaloglycin were reported at pH = 7.30 ± 0.01 in = 1.0 molL-1 NaClO4 used as supporting electrolyte at 25.0°C. Kinetic parameters viz. transfer coefficient (α), degree of irreversibility (λ) and rate constant (k) were determined. The study showed that 'Transition state' behaves between reactant (O) and product (R) response to applied potential. The stability constants varied from 2.14 to 10.31 showing that these drugs or their complexes could be used against Zn toxicity.
Keywords : Electrode kinetics; zinc-antibiotics-cephaloglycin system; binary and ternary complexes.