Revista do Colégio Brasileiro de Cirurgiões
versão On-line ISSN 1809-4546
RIVOIRE, Henri Chaplin et al. Tubal sterilization with synthetic surgical adhesive: experimental study. Rev. Col. Bras. Cir. [online]. 2003, vol.30, n.5, pp. 337-343. ISSN 1809-4546. http://dx.doi.org/10.1590/S0100-69912003000500003.
BACKGROUND: Study of the patency of the uterine tube of rabbits submitted to the transvaginal approach application of n-butyl-2-cyanoacrylate. METHODS: Twenty rabbits were used (Orictolagus cuniculus) of the lineage New Zealand, distributed in two groups, 1 (control) and 2 (try). Control group was submitted to the technique for sterilization through the method proposed by Pomeroy and the group experiment had the application of 0,25mL of the surgical adhesive n-butyl-2-cyanoacrylate in the isthmus of uterine tube, via transvaginal. After four weeks and four time mated and the clinical diagnosis of gestation appearance, they were submitted to three patency tests: histerosalpingography (in vivo), patency test with color metilen blue (in vitro) and test of breaking pressure (in vitro). Digital computerized morfometry was accomplished to measure the diameter of tubes, mucous membrane and miosalpinx. RESULTS: The results showed leak in only one uterine tube of the group 2, although the sticker was present in the isthmus of uterine tube. Statistical significancy was shown by the morfometry that showed increase in the measures of the diameter tube, of mucous membrane and of miosalpinx, that we considered to be for the presence of the polymeric formed by the adhesive, not cellular damages. CONCLUSIONS: We concluded that the application n-butyl-2-cyanoacrylate of transvaginal route in the uterine tubes of rabbits is so effective for sterilization as the method of Pomeroy.
Palavras-chave : Fallopian tubes; Sterilization, tubal; Tissue adhesives; Cyanoacrylates; Rabbits.