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Revista Brasileira de Ginecologia e Obstetrícia

Print version ISSN 0100-7203On-line version ISSN 1806-9339

Abstract

ELEUTERIO JUNIOR, José; CAVALCANTE, Diane Isabelle Magno; FERREIRA, Francisco Valdeci de Almeida  and  MEDEIROS, Francisco das Chagas. Estrogen and progesterone receptors in peritoneal fluid cell sediment in pelvic endometriosis: immunocytochemical study. Rev. Bras. Ginecol. Obstet. [online]. 2001, vol.23, n.2, pp.83-86. ISSN 0100-7203.  http://dx.doi.org/10.1590/S0100-72032001000200004.

Purpose: to evaluate the expression of estrogen (ER) and progesterone (PR) receptors in smears of peritoneal fluid sediment from patients with and without endometriosis. Methods: immunocytochemical study of ER and PR in smears of peritoneal fluid sediment in 19 cases with endometriosis and 7 without (control group), observing their expression. The data were submitted to Student's t-test to evaluate statistical significance. Results: in 84.6% of the cases with endometriosis, endometrial-like cells expressed ER (mean = 4.1%). In cases without endometriosis there was ER expression in 42.9%, with a mean of 4.5% (p = 0.1706). PR was expressed in only one case of endometriosis, with an endometrioma rupture history. Conclusions: there was no difference of ER expression between cases with endometriosis and the control group, in contrast to tissue behavior. Further cases must be studied for a better evaluation of this enigmatic mechanism of hormonal receptors in exfoliated cells.

Keywords : Endometriosis; Receptors; estrogen and progesterone; peritoneal fluid cells; Immunocytochemistry.

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