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Revista Brasileira de Ginecologia e Obstetrícia
On-line version ISSN 1806-9339
REHDER, Patricia Moretti et al. Antiphospholipid antibodies in gestational and pregestational diabetic women. Rev. Bras. Ginecol. Obstet. [online]. 2006, vol.28, n.3, pp. 179-183. ISSN 1806-9339. http://dx.doi.org/10.1590/S0100-72032006000300007.
PURPOSE: to diagnose and treat diabetic pregnant women with antiphospholipid antibodies and to describe the gestational and perinatal results. METHODS: we evaluated 56 gestational and pregestational diabetic women who were attended at one specialized prenatal care unit, between July 2003 and March 2004. All of them had a blood test to quantify antiphospholipid antibodies. If positive, they were treated with heparin and aspirin at low doses and the usual treatment for diabetes. We calculated the prevalence and 95% confidence interval for all and also those for the pregestational ones. The characteristics of the pregnancies and the newborns are described. RESULTS: antiphospholipid antibodies prevalence among the diabetic pregnant women was 7% (95% CI - 0.1 to 13.9). Among pregestational diabetic women it was 12% (95% CI - 0.2 to 23.3). Among the diabetic women with antiphospholipid antibodies the duration of disease was five years or more. Maternal age in positive antiphospholipid antibodies diabetics ranged from 27 to 38 years; one was primiparous, another was secundiparous and two were multiparous. CONCLUSION: antiphospholipid antibodies prevalence in diabetic pregnant women was similar to that in the general population and lower than that of the pregestational diabetic women.
Keywords : High-risk pregnancy; Pregnancy in diabetes; Antibodies, antiphospolipid; Antiphospholipid syndrome; Diabetes mellitus.