Pesquisa Veterinária Brasileira
versión impresa ISSN 0100-736X
PEREIRA, Ingrid A. et al. Susceptibility to azithromycin of bacteria isolated from infectious processes in dogs and cats. Pesq. Vet. Bras. [online]. 2009, vol.29, n.2, pp. 153-156. ISSN 0100-736X. http://dx.doi.org/10.1590/S0100-736X2009000200012.
The susceptibility pattern to azithromycin of bacterial pathogens from various infectious sites, and the in vitro activity and minimum inhibitory concentration (MIC) of azithromycin were studied. Tests such as disc diffusion and broth microdilution detected respectively 48.6% and 55% of resistant Staphylococcus spp., and 55.3% and 72.7% resistant gram-negative rods. MIC50 for S. aureus was 4.0mg/mL, that for S. intermedius was 1.0mg/mL, for coagulase-negative Staphylococcus e"512mg/mL, and for gram-negative rods 256mg/mL. Fifteen percent (9/60) of oxacilin-resistant, multidrug-resistant and mecA-positive Staphylococcus spp. isolates were also azithromycin resistant. The dissemination of multidrug resistant bacteria points out to the need of antimicrobial evaluation activity in order to select the best indicated drug and thus minimizing therapeutic failures in veterinary practice.
Palabras llave : Diseases of dogs and cats; bacterial diseases; bacterial antibiotic resistance; azithromycin.