SciELO - Scientific Electronic Library Online

 
vol.37 issue7Antiviral and virucidal activity of hydroalcoholic extracts of propolis brown, green and jataí bees (Tetragonisca angustula) against Bovine Herpesvirus Type-1 (BoHV-1) and Bovine Viral Diarrhea Virus (BVDV)Experimental poisoning by Niedenzuella stannea (Malpighiaceae) in sheep author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

Share


Pesquisa Veterinária Brasileira

Print version ISSN 0100-736XOn-line version ISSN 1678-5150

Abstract

GONCALVES, Maiara A. et al. Vascular injury in spontaneous subacute toxicosis caused by organic arsenic in cattle. Pesq. Vet. Bras. [online]. 2017, vol.37, n.7, pp.676-680. ISSN 0100-736X.  https://doi.org/10.1590/s0100-736x2017000700004.

Monosodium methanearsonate (MSMA) is an organic form of arsenic present in the formulations of some herbicides. Accidental ingestion of pasture contaminated with arsenic may lead to toxicosis in cattle. Almost 200 head of cattle maintained in an area sprayed with MSMA presented with intense diarrhea and dehydration after grazing. Subsequently, 16 of these animals died. Toxic levels of arsenic (>1.5μg/g) were detected in the kidney, liver, urine, and skeletal muscle of 6 animals. At gross inspection were observed multifocal to coalescent ulcers in the mucosa from on the forestomachs associated with hemorrhagic areas and marked wall edema. Microscopic examination mainly showed fibrinoid necrosis of vessels with multifocal thrombosis associated with ischemic infarction that were characterized by large transmural necrotic areas in the forestomachs. The clinical and pathological changes interestingly showed that this form of arsenic although considered less toxic, has caused severe vascular injury in forestomachs of cattle.

Keywords : Toxicosis; organic arsenic; cattle; MSMA; arsenic poisoning; vascular necrosis.

        · abstract in Portuguese     · text in English     · English ( pdf )