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Brazilian Journal of Medical and Biological Research

On-line version ISSN 1414-431X

Abstract

CARVALHO, L. Alberto V.; CASTRO, J.C.  and  CARVALHO, L. Antonio V.. Measuring higher order optical aberrations of the human eye: techniques and applications. Braz J Med Biol Res [online]. 2002, vol.35, n.11, pp. 1395-1406. ISSN 1414-431X.  http://dx.doi.org/10.1590/S0100-879X2002001100019.

In the present paper we discuss the development of "wave-front", an instrument for determining the lower and higher optical aberrations of the human eye. We also discuss the advantages that such instrumentation and techniques might bring to the ophthalmology professional of the 21st century. By shining a small light spot on the retina of subjects and observing the light that is reflected back from within the eye, we are able to quantitatively determine the amount of lower order aberrations (astigmatism, myopia, hyperopia) and higher order aberrations (coma, spherical aberration, etc.). We have measured artificial eyes with calibrated ametropia ranging from +5 to -5 D, with and without 2 D astigmatism with axis at 45º and 90º. We used a device known as the Hartmann-Shack (HS) sensor, originally developed for measuring the optical aberrations of optical instruments and general refracting surfaces in astronomical telescopes. The HS sensor sends information to a computer software for decomposition of wave-front aberrations into a set of Zernike polynomials. These polynomials have special mathematical properties and are more suitable in this case than the traditional Seidel polynomials. We have demonstrated that this technique is more precise than conventional autorefraction, with a root mean square error (RMSE) of less than 0.1 µm for a 4-mm diameter pupil. In terms of dioptric power this represents an RMSE error of less than 0.04 D and 5º for the axis. This precision is sufficient for customized corneal ablations, among other applications.

Keywords : Optical aberrations; Corneal topography; Zernike polynomials; Refractive surgery.

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