Healthy |
RS2 high amylose content vs. Placebo |
n=12 Acute |
Bread containing different % of RS |
Decreased AUC , glucose peak and peak of insulin secretion |
Ekström et al. (2013) Ekström, L. M., Björck, I. M., & Ostman, E. M. (2013). On the possibility to affect the course of glycaemia, insulinaemia, and perceived hunger/satiety to bread meals in healthy volunteers. Food & Function, 4(4), 522-529. http://dx.doi.org/10.1039/c2fo30251a. PMid:23334658. http://dx.doi.org/10.1039/c2fo30251a ...
|
Healthy |
RS2 high amylose content vs. Placebo |
n=10 Parallel 4 weeks |
30 g/day |
Increased IS
|
Robertson et al. (2005) Robertson, M. D., Bickerton, A. S., Dennis, A. L., Vidal, H., & Frayn, K. N. (2005). Insulin-sensitizing effects of dietary resistant starch and effects on skeletal muscle and adipose tissue metabolism. The American Journal of Clinical Nutrition, 82(3), 559-567. http://dx.doi.org/10.1093/ajcn/82.3.559. PMid:16155268. http://dx.doi.org/10.1093/ajcn/82.3.559...
|
Healthy |
UBF vs. placebo |
n=11 Parallel 6 weeks |
8 g /day 3 times a week |
Improvement observed in: - Fasting insulin, - HOMA IR
|
Sardá et al. (2016) |
MS
|
RS2 high amylose content vs. Placebo |
n=10 Single blind. Parallel 12 weeks |
40 g/day (in 2 sachets) |
IS measured by glucose Clamp increased 19% in the RS group (p=0.023). IS dropped 14% in the placebo group and was not significant |
Johnston et al. (2010) |
Obese MS
|
RS2 high amylose content vs. Placebo |
M=11, W=22 Double Blind. Crossover. 4 wk. treatment and 3 wk. washout
|
15 g/day (in 2 sachets) |
- Improved IS5 in men - No change observed in women |
Maki et al. (2012) Maki, K. C., Pelkman, C. L., Finocchiaro, E. T., Kelley, K. M., Lawless, A. L., Schild, A. L., & Rains, T. M. (2012). Resistant starch from high-amylose maize increases insulin sensitivity in overweight and obese men. The Journal of Nutrition, 142(4), 717-723. http://dx.doi.org/10.3945/jn.111.152975. PMid:22357745. http://dx.doi.org/10.3945/jn.111.152975...
|
MS
|
RS2 high amylose content vs. Placebo |
M=8, W=7 Single Blind. Crossover 8 week treatment and 8 week washout
|
40 g/day (in 2 sachets) |
Improvement in: - Fasting glucose, - Fasting insulin - HOMA IR
|
Robertson et al. (2012) Robertson, M. D., Wright, J. W., Loizon, E., Debard, C., Vidal, H., Shojaee-Moradie, F., Russell-Jones, D., & Umpleby, A. M. (2012). Insulin-sensitizing effects on muscle and adipose tissue after dietary fiber intake in men and women with metabolic syndrome. The Journal of Clinical Endocrinology and Metabolism, 97(9), 3326-3332. http://dx.doi.org/10.1210/jc.2012-1513. PMid:22745235. http://dx.doi.org/10.1210/jc.2012-1513 ...
|
IR
|
RS2 high amylose content vs. Placebo |
IS (n=9), IR (n=14) Double Blind. Crossover 4 week treatment and 4 week washout
|
30 g/day (biscuits) |
Improved IS5 only in the IR group. |
Gower et al. (2016) Gower, B. A., Bergman, R., Stefanovski, D., Darnell, B., Ovalle, F., Fisher, G., Sweatt, S. K., Resuehr, H. S., & Pelkman, C. (2016). Baseline insulin sensitivity affects response to high-amylose maize resistant starch in women: a randomized, controlled trial. Nutrition & Metabolism, 13(1), 2. http://dx.doi.org/10.1186/s12986-016-0062-5. PMid:26766961. http://dx.doi.org/10.1186/s12986-016-00...
|
DT2 (stable) |
RS2 high amylose content vs. Placebo |
n=17 |
Cross-over 12 wk. 40 g/day |
No change observed: in IS; Fasting glucose; HOMA (AUC: p=0.036) |
Bodinham et al. (2014) Bodinham, C. L., Smith, L., Thomas, E. L., Bell, J. D., Swann, J. R., Costabile, A., Russell-Jones, D., Umpleby, A. M., & Robertson, M. D. (2014). Efficacy of increased resistant starch consumption in human type 2 diabetes. Endocrine Connections, 3(2), 75-84. http://dx.doi.org/10.1530/EC-14-0036. PMid:24671124. http://dx.doi.org/10.1530/EC-14-0036 ...
|