Diskin (1212 Diskin CJ, Stokes TJ, Dansby LM, Radcliff L, Carter TB. Removal of methotrexate by peritoneal dialysis and hemodialysis in a single patient with end-stage renal disease. Am J Med Sci 2006;332:156-8.)
|
M |
60 |
PD |
RA |
10 |
2 |
20 |
0.53 |
300 |
Dead |
Chess (1313 Chess JA, Scholey G, Mikhail AI. Neutropenia associated with the use of low-dose methotrexate in a peritoneal dialysis patient. Nephrol Dial Transplant 2004;19:2158-9.)
|
M |
64 |
PD |
Psoriasis |
- |
- |
35 |
- |
300 |
Dead |
Sun (1414 Sun CY, Lin HC, Chen YC, Tsai CR, Wu MS. Leukemoid reaction after methotrexate-induced pancytopenia in a patient undergoing continuous ambulatory peritoneal dialysis. Chang Gung Med J 2006;29:513-7.)
|
F |
33 |
PD |
Lupus Arthritis |
5.0 |
2 |
25 |
- |
600 |
Recovered |
Liu WC (1515 Liu WC, Chen HC, Chen JS. Clinical dilemma over low-dose methotrexate therapy in dialysis patients: a case report and review of literature. Iran J Kidney Dis 2014;8:81-4.)
|
F |
61 |
PD |
Eczema |
7.5 |
3 |
22.5 |
0.08 |
30 |
Recovered |
Elman (1616 Ellman MH, Ginsberg D. Low-dose methotrexate and severe neutropenia in patients undergoing renal dialysis. Arthritis Rheum 1990;33:1060-1.)
|
F |
52 |
HD |
RA |
2.5 |
Single dose |
2.5 |
0.13 |
500 |
Dead |
Elman (1616 Ellman MH, Ginsberg D. Low-dose methotrexate and severe neutropenia in patients undergoing renal dialysis. Arthritis Rheum 1990;33:1060-1.)
|
F |
47 |
HD |
Systemic sclerosis |
2.5 |
Single dose |
2.5 |
- |
1500 |
Recovered |
Nakamura (1717 Nakamura M, Sakemi T, Nagasawa K. Severe pancytopenia caused by a single administration of low dose methotrexate in a patient undergoing hemodialysis. J Rheumatol 1999;26:1424-5.)
|
M |
57 |
HD |
RA |
5.0 |
Single dose |
5.0 |
0.03 |
100 |
Recovered |
Chatham (1818 Chatham WW, Morgan SL, Alarcón GS. Renal failure: a risk factor for methotrexate toxicity. Arthritis Rheum 2000;43:1185-6.)
|
M |
49 |
HD |
Myositis |
- |
2 |
- |
- |
90 |
Recovered |
Chatham (1818 Chatham WW, Morgan SL, Alarcón GS. Renal failure: a risk factor for methotrexate toxicity. Arthritis Rheum 2000;43:1185-6.)
|
M |
52 |
HD |
Myositis |
5.0 |
Single dose |
5.0 |
- |
2200 |
Recovered |
Chatham (1919 Basile C, Montanaro A, Semeraro A. Should low-dose methotrexate therapy be prescribed to dialysis patients? Nephrol Dial Transplant 2002;17:530-1.)
|
F |
61 |
HD |
Psoriasis |
2.5 |
3 |
7.5 |
- |
50 |
Dead |
Boulanger (1111 Boulanger H, Launay-Vacher V, Hierniaux P, Fau JB, Deray G. Severe methotrexate intoxication in a haemodialysis patient treated for rheumatoid arthritis. Nephrol Dial Transplant 2001;16:1087.)
|
F |
60 |
HD |
RA |
5.0 |
2 |
10.0 |
- |
1300 |
Recovered |
Basile (1919 Basile C, Montanaro A, Semeraro A. Should low-dose methotrexate therapy be prescribed to dialysis patients? Nephrol Dial Transplant 2002;17:530-1.)
(2020 Yang CP, Kuo MC, Guh JY, Chen HC. Pancytopenia after low dose methotrexate therapy in a hemodialysis patient: case report and review of literature. Ren Fail 2006;28:95-7.)
|
F |
74 |
HD |
RA |
5.0 |
2 |
10.0 |
- |
1700 |
Recovered |
Boey (99 Boey O, Van Hooland S, Woestenburg A, Van der Niepen P, Verbeelen D. Methotrexate should not be used for patients with end-stage kidney disease. Acta Clin Belg 2006;61:166-9.)
|
M |
66 |
HD |
Psoriasis |
5.0 |
2 |
10.0 |
0.03 |
70 |
Recovered |
Yang (2020 Yang CP, Kuo MC, Guh JY, Chen HC. Pancytopenia after low dose methotrexate therapy in a hemodialysis patient: case report and review of literature. Ren Fail 2006;28:95-7.)
|
F |
55 |
HD |
RA |
7.5 |
12 |
90.0 |
0.11 |
400 |
Dead |
Seneschal (2121 Seneschal J, Héliot-Hostein I, Taieb A. Pancytopenia induced by low-dose methotrexate in a haemodialysis patient treated for bullous pemphigoid. J Eur Acad Dermatol Venereol 2007;21:1135-6.)
|
M |
76 |
HD |
PB |
5.0 |
1.5 |
7.5 |
0.47 |
550 |
Dead |
Cheung (2222 Cheung KK, Chow KM, Szeto CC, Tai MH, Kwan BC, Li PK. Fatal pancytopenia in a hemodialysis patient after treatment with low-dose methotrexate. J Clin Rheumatol 2009;15:177-80.)
|
M |
56 |
HD |
Psoriasis |
2.5 |
Single dose |
2.5 |
0.06 |
60 |
Dead |
Liu H. (2323 Liu H, Liu F, Zhang M, Yan W, Sang H. Combined acute interstitial pneumonitis and pancytopenia induced by low-dose methotrexate in a hemodialysis patient treated for bullous pemphigoid. An Bras Dermatol 2015;90:43-5.)
|
M |
48 |
HD |
PB |
10 |
2 |
20 |
0.14 |
1800 |
Recovered |
Mima (2424 Mima A, Nagahara D, Tansho K. Methotrexate induced pneumatosis intestinalis under hemodialysis patient. Hemodial Int 2017;21:E9-E12.)
|
M |
46 |
HD |
RA |
- |
- |
- |
- |
690 |
Recovered |
Flynn (2525 Flynn KN, Johnson MS, Brink WC, Smith DL. Pancytopenia, mucositis, and hepatotoxicity after intralesional methotrexate injection in a patient treated with peritoneal dialysis. Am J Health Syst Pharm 2012;69:578-82.)
|
M |
68 |
PD |
CA squamous cells |
2.5 intra-lesion |
Single dose |
25 |
0.03 |
600 |
Recovered |
Current report |
M |
68 |
PD |
vasculitis |
7.5 |
2 |
15 |
0.005 |
600 |
Recovered |