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Archives of Clinical Psychiatry (São Paulo)

versão impressa ISSN 0101-6083versão On-line ISSN 1806-938X

Resumo

BARCELOS, Ricardo et al. Vascular depression in elderly: response to treatment with antidepressant associated to cholinesterase inhibitor. Rev. psiquiatr. clín. [online]. 2007, vol.34, n.6, pp.290-293. ISSN 1806-938X.  http://dx.doi.org/10.1590/S0101-60832007000600006.

CONTEXT: Among neuropsychiatric disorders caused by cerebrovascular factors, vascular depression is diagnosed in a small degree by general practitioners, causing morbid-mortality increase in elderly. CASE REPORT: That is a case of a 67 year-old-man with partial response after treatment with a Selective Serotonin Receptors Inhibitor, and severe autonomic adverse effects with other antidepressants. The addition of rivastigmine to citalopram resulted in a therapeutic success, with a reduction of 23 to 7 points on the Hamilton Depressive Scale (HAM-D). DISCUSSION: The result obtained brings new perspectives to the treatment of vascular depression, providing that randomized controlled trials with larger sample sizes confirm the positive effect of the addition of a cholinesterase inhibitor to antidepressants in the treatment of these patients.

Palavras-chave : Vascular depression; vascular dementia; Alzheimer's disease; stroke; neuroimaging.

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