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Archives of Clinical Psychiatry (São Paulo)

versão impressa ISSN 0101-6083

Resumo

OLIVEIRA, Virginia et al. Carbon nanotubes applied in neuroscience: prospects and challenges. Rev. psiquiatr. clín. [online]. 2011, vol.38, n.5, pp.201-206. ISSN 0101-6083.  http://dx.doi.org/10.1590/S0101-60832011000500006.

BACKGROUND: Carbon nanotubes (CNTs) are the most promising nanomaterials for therapeutic application in neurodegenerative diseases. Potential applications include systems for controlled drug delivery, electrical interfaces and substrates for cell growth. OBJECTIVE: To describe the state of art, prospects and challenges of applying CNTs in neuroscience. METHODS: There has been systematic search in Medline, Lilacs and SciELO, using the keywords "carbon nanotubes", "drug delivery", "electrical interface", "tissue regeneration", "neuroscience", "nanotechnology" and "biocompatibility", properly grouped. RESULTS: The literature review showed controversies in studies on the biocompatibility of CNTs, although it has ratified its potential for neuromedicine and neuroscience. DISCUSSION: These results highlight the need for modeling studies on the applications and interactions of nanostructures with biological systems.

Palavras-chave : Carbon nanotubes; drug delivery; electrical interface; tissue regeneration; neurobiology.

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