Social and Anthropometric Explanatory Variables |
Age |
Integer number (years) |
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Body mass index (BMI) |
Continuous measurement (kg/m2) |
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Gender |
Binomial: male or female |
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Education level |
Ordinal classification with five categories: illiterate, primary school (also incomplete), high school (also incomplete), college education (also incomplete), and post-graduation |
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Smoking |
Nominal classification with three categories: non-smoker, former smoker, and smoker |
Explanatory Variables from Previous Cardiovascular History |
Previous myocardial infaction (PMI) |
Binomial classification: yes or no |
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Any previous revascularization (APR) |
Binomial classification: yes or no |
Clinic and Laboratory Explanatory Variables upon Hospital Admission |
Type of acute coronary syndrome (ACS) |
Nominal classification with three categories: unstable angina, acute myocardial infarction without ST-segment elevation, and acute myocardial infarction with ST-segment elevation |
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Heart Rate |
Integer number |
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Killip classification (Killip) |
Ordinal classification with four categories: class I, class II, class III, and class IV |
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Creatinine |
Continuous measurement |
Diagnostic Explanatory Variables |
Systemic arterial hypertension (SAH) |
Binomial classification: normal or elevated (systolic arterial pressure equal to or above 140 mmHg or diastolic pressure equal to or above 90 mmHg or an individual who takes an anti-hypertensive medication) |
|
Total cholesterol |
Binomial classification: normal or elevated (cholesterol above 200 mg/dl or an individual who takes a lipid-lowering medication) |
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Triglyceride |
Binomial classification: normal or elevated (triblycerides above 150 mg/dl or an individual who takes a lipid-lowering medication) |
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HDL cholesterol |
Binomial classification: normal or low (HDL cholesterol below 40 mg/dl or an individual who takes a lipid-lowering medication) |
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Diabetes mellitus |
Binomial classification: negative or positive (fasting glycemia equal to or above 126 mg/dl or prior use of an oral hypoglycemic agent or insulin) |
Genetic Explanatory Variables |
DD genotype of the Angiotensin I-Converting-Enzyme gene polymorphism(DD genotype) |
Binomial classification: present or absent |
|
DI genotype of the Angiotensin I-Converting-Enzyme gene polymorphism (DI genotype) |
Binomial classification: present or absent |
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II genotype of the Angiotensin I-Converting-Enzyme gene polymorphism (II genotype) |
Binomial classification: present or absent |
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MM genotype of the M235T polymorphism of the Angiotensinogen gene (MM genotype) |
Binomial classification: present or absent |
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MT genotype of the M235T polymorphism of the Angiotensinogen gene (MT genotype) |
Binomial classification: present or absent |
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TT genotype of the M235T polymorphism of the Angiotensinogen gene (TT genotype) |
Binomial classification: present or absent |
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E2E2 genotype of the Apolipoprotein E gene polymorphism (E2E2 genotype) |
Binomial classification: present or absent |
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E2E3 genotype of the Apolipoprotein E gene polymorphism (E2E3 genotype) |
Binomial classification: present or absent |
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E2E4 genotype of the Apolipoprotein E gene polymorphism (E2E4 genotype) |
Binomial classification: present or absent |
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E3E3 genotype of the Apolipoprotein E gene polymorphism (E3E3 genotype) |
Binomial classification: present or absent |
|
E3E4 genotype of the Apolipoprotein E gene polymorphism (E3E4 genotype) |
Binomial classification: present or absent |
Response Variable |
Death during the hospital stay |
Binomial classification: yes or no |