Revista Brasileira de Coloproctologia
versão impressa ISSN 0101-9880
FORTES, Renata Costa; RECOVA, Viviane La corte; MELO, Andresa Lima e NOVAES, Maria Rita Carvalho Garbi. Quality of life of patients with colorectal cancer on dietary supplementation with Agaricus sylvaticus fungus: after six months of segment: randomized and placebo-controlled clinical trial. Rev bras. colo-proctol. [online]. 2007, vol.27, n.2, pp. 130-138. ISSN 0101-9880. http://dx.doi.org/10.1590/S0101-98802007000200002.
INTRODUCTION: Gastrointestinal cancer jeopardizes the quality of life through physiological, metabolic and psychological alterations. Medicinal fungus may boost the quality of life of patients with cancer. OBJECTIVE: To evaluate the effects of the dietary supplementation with Agaricus sylvaticus fungus in relation to the quality of life in patients with colorectal cancer during post-surgery phase. METHODOLOGY: Randomized, double-blind, placebo-controlled clinical trial carried out at the Federal District Hospital - Brazil, for six months. Samples of 56 enrolled patients (24 men and 32 women), stadiums phase I, II and III, separated as placebo and Agaricus sylvaticus (30mg/kg/day) supplemented groups: In order to evaluate indicators for quality of life, it was used form-standard and direct anamnese-standard. The method of analysis for results was qualitative and descriptive, using the Microsoft Excel 2003 and Epi Info 2004 programs. RESULTS: After six months of treatment, it was observed an increase of adhesion to physical activity; improved disposition and good mood, reduction of complaints, pains, and alterations of sleep such as insomnia and bad nights of sleep when Agaricus sylvaticus and placebo groups were compared. CONCLUSION: The results suggest that the dietary supplementation with Agaricus sylvaticus may improve the quality of life of patients with colorectal adenocarcinoma in post-surgery phase.
Palavras-chave : Agaricus sylvaticus fungus; quality of life; colorectal cancer; metabolic alterations; physiologic alterations.