Arquivo Brasileiro de Medicina Veterinária e Zootecnia
On-line version ISSN 1678-4162
RIBEIRO, M.G. et al. Cytotoxic necrotizing factor in Escherichia coli strain isolated from clinical bovine mastitis. Arq. Bras. Med. Vet. Zootec. [online]. 2002, vol.54, n.6, pp. 648-650. ISSN 1678-4162. http://dx.doi.org/10.1590/S0102-09352002000600015.
This report describes the production of cytotoxic necrotizing factor (CNF) by an Escherichia coli strain isolated from clinical bovine mastitis with clinical signs of toxemia The animal had hemorrhages and necrosis of the mammary glands, and died within 24 hours after the onset of clinical signs. In addition to CNF identification, alpha-haemolysin and siderophores production were also characterized in this strain. This report reinforce the association of CNF and alpha-haemolysin production in E. coli virulence associated with clinical cases of severe bovine mastitis.
Keywords : Bovine mastitis; Escherichia coli; virulence factors; cytotoxic necrotizing factor.