Arquivo Brasileiro de Medicina Veterinária e Zootecnia
versão On-line ISSN 1678-4162
SPILKI, F.R. et al. Co-infections with bovine herpesvirus type 5 and bovine viral diarrhoea virus. Arq. Bras. Med. Vet. Zootec. [online]. 2006, vol.58, n.5, pp. 699-707. ISSN 1678-4162. http://dx.doi.org/10.1590/S0102-09352006000500001.
During a series of experiments attempting to reproduce clinically apparent bovine herpesvirus type 5 (BoHV-5) infections, a group of calves was inadvertently infected with bovine viral diarrhoea virus (BVDV). Another group of calves was infected with BoHV-5 only. This paper reports the outcome of such infections. Two out of six calves solely infected with BoHV-5 displayed moderate to severe clinical signs. Three out of four calves of the group co-infected with BoHV-5 and BVDV developed severe clinical signs, two of them died. BoHV-5 virus was isolated to higher titres and for a longer period from the group of calves infected with both viruses. These results suggest that BVDV may enhance clinical signs induced by BoHV-5 and may also play a role in extending the period of BoHV-5 shedding.
Palavras-chave : BoHV-5; BVDV; co-infection; experimental inoculation.