SciELO - Scientific Electronic Library Online

 
vol.23 número10Adaptação transcultural de índices de qualidade de vida relacionada à saúde bucalAnálise comparativa de embalagens secundárias e bulas de medicamentos contendo Panax ginseng C. A. Meyer índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados

Journal

Artigo

Indicadores

Links relacionados

Compartilhar


Cadernos de Saúde Pública

versão impressa ISSN 0102-311Xversão On-line ISSN 1678-4464

Resumo

FREITAS, Letícia Figueira; CHAVES, Gabriela Costa; WANNMACHER, Lenita  e  OSORIO-DE-CASTRO, Claudia Garcia Serpa. Uncomplicated Plasmodium vivax and P. falciparum malaria in Brazil: evidence on single and combined drug treatments recommended by official guidelines. Cad. Saúde Pública [online]. 2007, vol.23, n.10, pp.2285-2294. ISSN 0102-311X.  https://doi.org/10.1590/S0102-311X2007001000004.

Malaria is the most important endemic parasitic disease in the world. Conditions are favorable for transmission of the disease in 60% of Brazil's territory. Over 500,000 cases per year are recorded in the country. However, the geographic distribution is uneven, which may explain differences in the efficacy and effectiveness of antimalarial drugs. We conducted an extensive literature review of antimalarial treatment in Brazil from 1980 to 2005 in order to identify evidence that might have been available for the 2001 Edition of the Malaria Treatment Manual, the official Ministry of Health guidelines. Only a few studies, of low methodological quality, were identified by the search. None of the studies would have been capable of generating evidence-based guidelines according to the current classification of levels of pharmacological and clinical evidence. Studies published after 2001 drew on more evidence and are expected to provide the basis for the next edition of the manual, due in 2007. References in the 2001 Edition were outdated, possibly perceived as traditional references in the field, but lacking in specificity for region, population, and/or type of malaria.

Palavras-chave : Treatment Protocols; Antimalarials; Malaria.

        · resumo em Português     · texto em Português     · Português ( pdf )

 

Creative Commons License Todo o conteúdo deste periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons