Cadernos de Saúde Pública
On-line version ISSN 1678-4464
CAMELO JUNIOR, José Simon et al. Newborn screening for galactosemia: a health economics evaluation. Cad. Saúde Pública [online]. 2011, vol.27, n.4, pp.666-676. ISSN 1678-4464. http://dx.doi.org/10.1590/S0102-311X2011000400006.
This study assesses the efficiency of the galactosemia add-on test in neonatal screening performed on regular Guthrie card blood spots. Based on estimated average incidence of galactosemia (1:19,984 newborns) in São Paulo State, Brazil, the study develops a cost-benefit analysis model, using a B/C ratio and a 9.25% annual interest rate in order to decapitalize the results. Sensitivity analysis is also performed, varying (as a function of the interest or discount rate) from 0 and 20% and according to the 95% confidence interval (1:7,494-1:59,953 newborns). The results show that the savings obtained by improved health of galactosemic patients detected early by add-on neonatal screening is superior to the costs (B/C=1.33), characterizing galactosemia add-on testing in neonatal screening as an efficient policy. The lower the prevailing interest rate in the economy, the more efficient the neonatal screening policy.
Keywords : Health Economics; Cost Efficiency Analysis; Neonatal Screening; Galactosemias.