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Jornal de Pneumologia
On-line version ISSN 1678-4642
FERREIRA, MARIA ANGÉLICA PIRES; GAZZANA, MARCELO BASSO; BARRETO, SÉRGIO SALDANHA MENNA and KNORST, MARLI MARIA. Hepatopulmonary syndrome in a patient with AIDS and virus C cirrhosis (viral cirrhosis type C). J. Pneumologia [online]. 2001, vol.27, n.1, pp. 52-55. ISSN 1678-4642. http://dx.doi.org/10.1590/S0102-35862001000100009.
Hepatopulmonary syndrome is characterized by a triad consisting of liver disorder, pulmonary vascular dilatation, and hypoxemia. No case of hepatopulmonary syndrome associated with AIDS has been reported so far. In this study, the authors report the case of a 43-year woman with AIDS and virus C cirrhosis taking prophylactic cotrimoxazole for pneumocystosis and retroviral therapy. Upon admission, the patient presented dyspnea, cyanosis, digital clubbing, vascular spiders, and normal chest examination. Chest X-ray revealed bilateral interstitial infiltration and evidenced increased alveolar-arterial gradient and liver function impairment. Intrapulmonary shunt was evidenced by contrast-enhanced echocardiography and radionuclide perfusion scanning, thus confirming hepatopulmonary syndrome.
Keywords : Hepatopulmonary syndrome; Acquired human immunodeficiency syndrome; Human viral hepatitis; Anoxemia; Liver cirrhosis.