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Jornal de Pneumologia
On-line version ISSN 1678-4642
JAMNIK, SÉRGIO; SANTORO, ILKA LOPES and UEHARA, CÉSAR. Comparative study of prognostic factors among longer and shorter survival patients with bronchogenic carcinoma. J. Pneumologia [online]. 2002, vol.28, n.5, pp. 245-249. ISSN 1678-4642. http://dx.doi.org/10.1590/S0102-35862002000500002.
Despite the improvements seen in the treatment of lung cancer, little has improved in the survival of these patients, and a great importance is attributed to the factors that have a role to play in such survival. Purpose: To check for possible prognostic factor differences in two populations of lung cancer patients, one of them with short survival (less than six months), and the other with longer survival (more than 24 months). Methods: From 1997 to 1999, 52 patients with histopathologic diagnosis of homogenous carcinoma were studied, and demographics, clinical parameters, smoking pattern, Karnofsky's index, disease staging, and laboratory dosing of lactic dehydrogenase, alkaline phosphatase, carcinoembryonic antigen, and calcium data were surveyed. Results: 29 patients had less than six month survival, and 23 had more than 24 month survival. The three most important factors for short survival were the low initial Karnofsky's index, loss of appetite, and high serum LDH levels. Conclusion: The three prognosis components are: current physical status, prior physical status, and current status of the disease.
Keywords : Bronchogenic carcinoma; Lung neoplasms; Squamous cell carcinoma; Adenocarcinoma; Small cell carcinoma.