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Revista Brasileira de Ortopedia
versão impressa ISSN 0102-3616
MALAVOLTA, Eduardo Angeli et al. Randomized controlled clinical trials in orthopedics: difficulties and limitations. Rev. bras. ortop. [online]. 2011, vol.46, n.4, pp.452-459. ISSN 0102-3616. http://dx.doi.org/10.1590/S0102-36162011000400018.
Randomized controlled clinical trials (RCTs) are considered to be the gold standard for evidence-based medicine nowadays, and are important for directing medical practice through consistent scientific observations. Steps such as patient selection, randomization and blinding are fundamental for conducting an RCT, but some additional difficulties are presented in trials that involve surgical procedures, as in common in orthopedics. The aim of this article was to highlight and discuss some difficulties and possible limitations on RCTs within the field of surgery.
Palavras-chave : Evidence-Based Medicine; Orthopedics; Randomized Controlled Trials as Topic; Comparative Study.