ABSTRACT
Background:
The best site for splenic implant was not defined, mainly evaluating the functionality of the implant.
Aim:
To evaluate the effects of autogenous splenic implantation on the subcutaneous tissue in the survival of splenectomized rats.
Method:
Twenty-one randomly assigned rats were studied in three groups (n=7): group 1 - manipulation of the abdominal cavity and preservation of the spleen; group 2 - total splenectomy; group 3 - splenectomy and implant of the tissue removed in the subcutaneous. The animals were followed for 90 days postoperatively.
Results:
There was a higher mortality in groups 2 (p=0.0072) and 3 (p=0.0172) in relation to group 1. There was no difference between groups 2 and 3 (p=0.9817).
Conclusion:
The splenic implant in the subcutaneous is ineffective in the survival of rats submitted to splenectomy.
HEADINGS:
Spleen; Splenectomy; Rats; Transplants
