Revista Brasileira de Farmacognosia
Print version ISSN 0102-695X
SA, Luiz Marques de. Some aspects of pharmacokinetics of Cannabis sativa L. (Marihuana) with emphasis on man. Rev. bras. farmacogn. [online]. 1989, vol.2-3-4, pp. 88-96. ISSN 0102-695X. http://dx.doi.org/10.1590/S0102-695X1989000100009.
This paper contains an analysis of the origin of the introduction of Cannabis in Brazil, the identify of its chemical components, mainly tetrahydrocannabinol responsible for the pharmacological effects of Cannabis. Toxicokinetic studies were developed in relation the amounts of marihuana consumed, characteristics of the user and origin of the drug. Absorption, distribution, storage, biotransformation and elimination of marihuana derived metabolites were studies.
Keywords : Cannabis sativa L.; Marihuana; Δ9THC; tetrahydocanabinol; Metabolism; Toxicology.