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Revista Brasileira de Farmacognosia

versión impresa ISSN 0102-695X


PIZZOLATTI, M. G; CRISTIANO, R.; MONACHE, F. D.  y  BRANCO, A.. Coumarinic artifacts isolated from Polygala paniculata L. (Polygalaceae). Rev. bras. farmacogn. [online]. 2002, vol.12, n.1, pp. 21-26. ISSN 0102-695X.

Fractionation of a chloroform extract of Polygala paniculata (Polygalaceae) on silica gel column chromatography yielded 7-methoxy-8-(1',2'-epoxy-3'-methyl-3'-butenyl)-coumarin (1) and two coumarinic artifacts (2a-2b). The reaction of 1 with EtOH/SiO2 at room temperature for 24 hours yielded 7-methoxy-8-(1'-hydroxy-2'-ethoxy-3'-methyl-3'-butenyl)-coumarin (2a) and 7-methoxy-8-(1'-ethoxy-2'-hydroxy-3'-methyl-3'-butenyl)-coumarin (2b). The structures have been determined by spectral data, including 2D NMR experiments.

Palabras clave : Polygala paniculata; Polygalaceae; coumarin; artifacts; NMR.

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