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Revista Brasileira de Farmacognosia
On-line version ISSN 1981-528X
SOARES, Carolina L.S. et al. Evaluation of the anti-inflammatory and analgesic activity of the crude hydroalcoholic extract of the zoanthid Palythoa caribaeorum (Duchassaing & Michelotti, 1860). Rev. bras. farmacogn. [online]. 2006, vol.16, n.4, pp. 463-468. ISSN 1981-528X. http://dx.doi.org/10.1590/S0102-695X2006000400004.
This work represents the first pharmacological analysis on the crude hydroalcoholic extract of Palythoa caribaeorum. The analgesic activity was assayed in acetic acid-induced writhing test and with the hot-plate test with mice; while the anti-inflammatory activity was evaluated in carrageenan-induced hind paw edema in the rat. The analysis suggested an analgesic activity in the Writhing test on the group treated with the crude extract (200 mg.kg-1 v.o.) with an abdominal contortions inhibition of 47,22 %.
Keywords : Palythoa caribaeorum; Zoantharia; Anthozoa; anti-inflammatory activity; analgesic activity.