Abstract

MELO, Marilia Martins; LUCIA, Maria  and  HABERMEHL, Gerhard G.. Plant extracts for topic therapy of Bothrops alternatus envenomation. Rev. bras. farmacogn. [online]. 2007, vol.17, n.1, pp.29-34. ISSN 1981-528X.  http://dx.doi.org/10.1590/S0102-695X2007000100007.

Two plants were investigated for their properties against the local effects of Bothrops alternatus venom in rabbits, namely Curcuma longa L. (Zingiberaceae) and Aristolochia cymbifera L. (Aristolochiaceae). The experiments showed that, Curcuma longa extract topic application was the most effective treatment against local symptoms (edema, hemorrhages and necrosis) caused by Bothrops venom, whereas the results with Aristolochia cymbifera L. were doubtful, because they led to a larger damaged area during the early phase of the inflammation process, besides skin mummification.

Keywords : Curcuma longa; Aristolochia cymbifera; Bothrops alternatus; snake venom.

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